Obsessive-Compulsive Disorder in Hospitalized Patients with Schizophrenia

Introduction: Comorbid obsessive-compulsive disorder (OCD) has been reported among patients with schizophrenia in other countries. But, the literature is not well-documented on this issue in Iran (Persia). The present study aimed to investigate the prevalence and severity of OCD and some of its rela...

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Main Authors: Mercedeh Samiei, Koorosh Hedayati, Arash Mirabzadeh Ardekani, Behrooz Dolatshahi, Reza Daneshmand, Roya Samadi
Format: Article
Language:English
Published: Iran University of Medical Sciences 2016-10-01
Series:Basic and Clinical Neuroscience
Subjects:
Online Access:http://bcn.iums.ac.ir/browse.php?a_code=A-10-992-6&slc_lang=en&sid=1
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author Mercedeh Samiei
Koorosh Hedayati
Arash Mirabzadeh Ardekani
Behrooz Dolatshahi
Reza Daneshmand
Roya Samadi
author_facet Mercedeh Samiei
Koorosh Hedayati
Arash Mirabzadeh Ardekani
Behrooz Dolatshahi
Reza Daneshmand
Roya Samadi
author_sort Mercedeh Samiei
collection DOAJ
description Introduction: Comorbid obsessive-compulsive disorder (OCD) has been reported among patients with schizophrenia in other countries. But, the literature is not well-documented on this issue in Iran (Persia). The present study aimed to investigate the prevalence and severity of OCD and some of its related factors in a group of patients with schizophrenia in Iran.  Methods: This is a cross-sectional study. A total of 150 hospitalized patients with schizophrenia were recruited at Razi Psychiatric Hospital in Tehran, Iran. Demographic and clinical checklists, as well as the Yale-Brown obsessive-compulsive scale (Y-BOCS), scale for assessment of negative symptoms (SANS), and scale for assessment of positive symptoms (SAPS) were administered to collect data. OCD was the dependent variable and independent variables included age, sex, severity of positive and negative symptoms, duration of schizophrenic disorder, the number of hospitalizations, and antipsychotic medications administered to them. Data were analyzed by analysis of variance (ANOVA), Chi-square, and T-test.  Results: Overall, 31.3% of patients had OCD with an average severity of 12.81(SD=10.27). The prevalence of OCD was not affected by the number of psychiatric hospitalizations for schizophrenia or the duration of schizophrenic disorder. The severity of OCD significantly reduced as the duration of schizophrenia and the severity of negative symptoms increased.  Conclusion: OCD was found among a considerable proportion of the study sample. OCD may be associated with exacerbating schizophrenic symptoms. Therefore, psychiatrists should consider the simultaneous treatment of OCD and schizophrenia. Further studies are suggested in this issue.
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spelling doaj.art-21d22d5d04c24f7fab128303e68f24252024-03-02T19:16:39ZengIran University of Medical SciencesBasic and Clinical Neuroscience2008-126X2228-74422016-10-0174323330Obsessive-Compulsive Disorder in Hospitalized Patients with SchizophreniaMercedeh Samiei0Koorosh Hedayati1Arash Mirabzadeh Ardekani2Behrooz Dolatshahi3Reza Daneshmand4Roya Samadi5 Department of Psychiatry, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Isfahan Psychiatric Hospital, Isfahan, Iran. Department of Psychiatry, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Psychiatry and Behavioral Sciences Research Center, Department of Psychiatry, Mashhad University of Medical Sciences, Mashhad, Iran. Introduction: Comorbid obsessive-compulsive disorder (OCD) has been reported among patients with schizophrenia in other countries. But, the literature is not well-documented on this issue in Iran (Persia). The present study aimed to investigate the prevalence and severity of OCD and some of its related factors in a group of patients with schizophrenia in Iran.  Methods: This is a cross-sectional study. A total of 150 hospitalized patients with schizophrenia were recruited at Razi Psychiatric Hospital in Tehran, Iran. Demographic and clinical checklists, as well as the Yale-Brown obsessive-compulsive scale (Y-BOCS), scale for assessment of negative symptoms (SANS), and scale for assessment of positive symptoms (SAPS) were administered to collect data. OCD was the dependent variable and independent variables included age, sex, severity of positive and negative symptoms, duration of schizophrenic disorder, the number of hospitalizations, and antipsychotic medications administered to them. Data were analyzed by analysis of variance (ANOVA), Chi-square, and T-test.  Results: Overall, 31.3% of patients had OCD with an average severity of 12.81(SD=10.27). The prevalence of OCD was not affected by the number of psychiatric hospitalizations for schizophrenia or the duration of schizophrenic disorder. The severity of OCD significantly reduced as the duration of schizophrenia and the severity of negative symptoms increased.  Conclusion: OCD was found among a considerable proportion of the study sample. OCD may be associated with exacerbating schizophrenic symptoms. Therefore, psychiatrists should consider the simultaneous treatment of OCD and schizophrenia. Further studies are suggested in this issue.http://bcn.iums.ac.ir/browse.php?a_code=A-10-992-6&slc_lang=en&sid=1Schizophrenia Obsessive-compulsive symptoms Iran Persian Gulf
spellingShingle Mercedeh Samiei
Koorosh Hedayati
Arash Mirabzadeh Ardekani
Behrooz Dolatshahi
Reza Daneshmand
Roya Samadi
Obsessive-Compulsive Disorder in Hospitalized Patients with Schizophrenia
Basic and Clinical Neuroscience
Schizophrenia
Obsessive-compulsive symptoms
Iran
Persian Gulf
title Obsessive-Compulsive Disorder in Hospitalized Patients with Schizophrenia
title_full Obsessive-Compulsive Disorder in Hospitalized Patients with Schizophrenia
title_fullStr Obsessive-Compulsive Disorder in Hospitalized Patients with Schizophrenia
title_full_unstemmed Obsessive-Compulsive Disorder in Hospitalized Patients with Schizophrenia
title_short Obsessive-Compulsive Disorder in Hospitalized Patients with Schizophrenia
title_sort obsessive compulsive disorder in hospitalized patients with schizophrenia
topic Schizophrenia
Obsessive-compulsive symptoms
Iran
Persian Gulf
url http://bcn.iums.ac.ir/browse.php?a_code=A-10-992-6&slc_lang=en&sid=1
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AT kooroshhedayati obsessivecompulsivedisorderinhospitalizedpatientswithschizophrenia
AT arashmirabzadehardekani obsessivecompulsivedisorderinhospitalizedpatientswithschizophrenia
AT behroozdolatshahi obsessivecompulsivedisorderinhospitalizedpatientswithschizophrenia
AT rezadaneshmand obsessivecompulsivedisorderinhospitalizedpatientswithschizophrenia
AT royasamadi obsessivecompulsivedisorderinhospitalizedpatientswithschizophrenia