Combined chemical peels versus trichloroacetic acid (TCA) for treating melasma: a split face study

Melasma is common skin condition presenting with hyperpigmentation. To evaluate the efficacy, tolerance, and complications of one session of combined chemical peels compared to traditional serial sessions of trichloroacetic acid (TCA) peeling in treating melasma. One session of combined chemical pee...

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Main Authors: Mona A. Atwa, Amal H. Ahmed, Hesham A. Nada, Shaimaa M. Refaey, Mohammad Jafferany, Mohamed L. Elsaie
Format: Article
Language:English
Published: Taylor & Francis Group 2022-02-01
Series:Journal of Dermatological Treatment
Subjects:
Online Access:http://dx.doi.org/10.1080/09546634.2020.1793888
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author Mona A. Atwa
Amal H. Ahmed
Hesham A. Nada
Shaimaa M. Refaey
Mohammad Jafferany
Mohamed L. Elsaie
author_facet Mona A. Atwa
Amal H. Ahmed
Hesham A. Nada
Shaimaa M. Refaey
Mohammad Jafferany
Mohamed L. Elsaie
author_sort Mona A. Atwa
collection DOAJ
description Melasma is common skin condition presenting with hyperpigmentation. To evaluate the efficacy, tolerance, and complications of one session of combined chemical peels compared to traditional serial sessions of trichloroacetic acid (TCA) peeling in treating melasma. One session of combined chemical peels was carried out at the left side of the face, while six sessions of TCA 15% peel were carried out at the right side of the face every 10 days. The Modified Melasma Area and Severity Index (MASI) score was calculated at baseline (before starting peeling sessions), after one month (at the fourth TCA peeling session), and after three months (one month after the last TCA peeling session). Both sides of the face showed gradual reduction in modified MASI score throughout sessions. By the end of the study, the TCA-treated side showed slightly lower mean modified MASI score than the combined chemical peels-treated side of the face; however this difference was not statistically significant, (p = .405). A single session of combined chemical peels is as effective as six sessions of TCA peel in treatment of melasma. Combined chemical peels can be used as a convenient, tolerable and time saving safe procedure for treating melasma.
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spelling doaj.art-21d6b673a85a428b8f8670f720f657b02023-09-15T14:23:07ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532022-02-0133295996410.1080/09546634.2020.17938881793888Combined chemical peels versus trichloroacetic acid (TCA) for treating melasma: a split face studyMona A. Atwa0Amal H. Ahmed1Hesham A. Nada2Shaimaa M. Refaey3Mohammad Jafferany4Mohamed L. Elsaie5Department of Dermatology, Suez Canal universityDepartment of Dermatology, Suez Canal universityDepartment of Dermatology, Suez Canal universityDepartment of Dermatology, Suez Canal universityCollege of Medicine, Central Michigan UnivesityDepartment of Dermatology, National Research CentreMelasma is common skin condition presenting with hyperpigmentation. To evaluate the efficacy, tolerance, and complications of one session of combined chemical peels compared to traditional serial sessions of trichloroacetic acid (TCA) peeling in treating melasma. One session of combined chemical peels was carried out at the left side of the face, while six sessions of TCA 15% peel were carried out at the right side of the face every 10 days. The Modified Melasma Area and Severity Index (MASI) score was calculated at baseline (before starting peeling sessions), after one month (at the fourth TCA peeling session), and after three months (one month after the last TCA peeling session). Both sides of the face showed gradual reduction in modified MASI score throughout sessions. By the end of the study, the TCA-treated side showed slightly lower mean modified MASI score than the combined chemical peels-treated side of the face; however this difference was not statistically significant, (p = .405). A single session of combined chemical peels is as effective as six sessions of TCA peel in treatment of melasma. Combined chemical peels can be used as a convenient, tolerable and time saving safe procedure for treating melasma.http://dx.doi.org/10.1080/09546634.2020.1793888melasmatrichloroacetic acid (tca)peeling
spellingShingle Mona A. Atwa
Amal H. Ahmed
Hesham A. Nada
Shaimaa M. Refaey
Mohammad Jafferany
Mohamed L. Elsaie
Combined chemical peels versus trichloroacetic acid (TCA) for treating melasma: a split face study
Journal of Dermatological Treatment
melasma
trichloroacetic acid (tca)
peeling
title Combined chemical peels versus trichloroacetic acid (TCA) for treating melasma: a split face study
title_full Combined chemical peels versus trichloroacetic acid (TCA) for treating melasma: a split face study
title_fullStr Combined chemical peels versus trichloroacetic acid (TCA) for treating melasma: a split face study
title_full_unstemmed Combined chemical peels versus trichloroacetic acid (TCA) for treating melasma: a split face study
title_short Combined chemical peels versus trichloroacetic acid (TCA) for treating melasma: a split face study
title_sort combined chemical peels versus trichloroacetic acid tca for treating melasma a split face study
topic melasma
trichloroacetic acid (tca)
peeling
url http://dx.doi.org/10.1080/09546634.2020.1793888
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