Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which caused Coronaviruses Disease 2019 (COVID-19) and a worldwide pandemic, is the seventh human coronavirus that has been cross-transmitted from animals to humans. It can be predicted that with continuous contact between humans and anim...
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MDPI AG
2021-07-01
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Series: | Microorganisms |
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Online Access: | https://www.mdpi.com/2076-2607/9/7/1479 |
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author | Xue Li Liying Zhang Si Chen Hongsheng Ouyang Linzhu Ren |
author_facet | Xue Li Liying Zhang Si Chen Hongsheng Ouyang Linzhu Ren |
author_sort | Xue Li |
collection | DOAJ |
description | Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which caused Coronaviruses Disease 2019 (COVID-19) and a worldwide pandemic, is the seventh human coronavirus that has been cross-transmitted from animals to humans. It can be predicted that with continuous contact between humans and animals, more viruses will spread from animals to humans. Therefore, it is imperative to develop universal coronavirus or pan-coronavirus vaccines or drugs against the next coronavirus pandemic. However, a suitable target is critical for developing pan-coronavirus antivirals against emerging or re-emerging coronaviruses. In this review, we discuss the latest progress of possible targets of pan-coronavirus antiviral strategies for emerging or re-emerging coronaviruses, including targets for pan-coronavirus inhibitors and vaccines, which will provide prospects for the current and future research and treatment of the disease. |
first_indexed | 2024-03-10T09:31:12Z |
format | Article |
id | doaj.art-21e6374d5d7247b9a1e25e65471bd321 |
institution | Directory Open Access Journal |
issn | 2076-2607 |
language | English |
last_indexed | 2024-03-10T09:31:12Z |
publishDate | 2021-07-01 |
publisher | MDPI AG |
record_format | Article |
series | Microorganisms |
spelling | doaj.art-21e6374d5d7247b9a1e25e65471bd3212023-11-22T04:26:22ZengMDPI AGMicroorganisms2076-26072021-07-0197147910.3390/microorganisms9071479Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging CoronavirusesXue Li0Liying Zhang1Si Chen2Hongsheng Ouyang3Linzhu Ren4Key Laboratory for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, 5333 Xi’An Road, Changchun 130062, ChinaKey Laboratory for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, 5333 Xi’An Road, Changchun 130062, ChinaKey Laboratory for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, 5333 Xi’An Road, Changchun 130062, ChinaKey Laboratory for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, 5333 Xi’An Road, Changchun 130062, ChinaKey Laboratory for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, 5333 Xi’An Road, Changchun 130062, ChinaSevere Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which caused Coronaviruses Disease 2019 (COVID-19) and a worldwide pandemic, is the seventh human coronavirus that has been cross-transmitted from animals to humans. It can be predicted that with continuous contact between humans and animals, more viruses will spread from animals to humans. Therefore, it is imperative to develop universal coronavirus or pan-coronavirus vaccines or drugs against the next coronavirus pandemic. However, a suitable target is critical for developing pan-coronavirus antivirals against emerging or re-emerging coronaviruses. In this review, we discuss the latest progress of possible targets of pan-coronavirus antiviral strategies for emerging or re-emerging coronaviruses, including targets for pan-coronavirus inhibitors and vaccines, which will provide prospects for the current and future research and treatment of the disease.https://www.mdpi.com/2076-2607/9/7/1479pan-coronavirustargetinhibitorvaccineepitope |
spellingShingle | Xue Li Liying Zhang Si Chen Hongsheng Ouyang Linzhu Ren Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses Microorganisms pan-coronavirus target inhibitor vaccine epitope |
title | Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses |
title_full | Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses |
title_fullStr | Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses |
title_full_unstemmed | Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses |
title_short | Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses |
title_sort | possible targets of pan coronavirus antiviral strategies for emerging or re emerging coronaviruses |
topic | pan-coronavirus target inhibitor vaccine epitope |
url | https://www.mdpi.com/2076-2607/9/7/1479 |
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