Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which caused Coronaviruses Disease 2019 (COVID-19) and a worldwide pandemic, is the seventh human coronavirus that has been cross-transmitted from animals to humans. It can be predicted that with continuous contact between humans and anim...

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Main Authors: Xue Li, Liying Zhang, Si Chen, Hongsheng Ouyang, Linzhu Ren
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/9/7/1479
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author Xue Li
Liying Zhang
Si Chen
Hongsheng Ouyang
Linzhu Ren
author_facet Xue Li
Liying Zhang
Si Chen
Hongsheng Ouyang
Linzhu Ren
author_sort Xue Li
collection DOAJ
description Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which caused Coronaviruses Disease 2019 (COVID-19) and a worldwide pandemic, is the seventh human coronavirus that has been cross-transmitted from animals to humans. It can be predicted that with continuous contact between humans and animals, more viruses will spread from animals to humans. Therefore, it is imperative to develop universal coronavirus or pan-coronavirus vaccines or drugs against the next coronavirus pandemic. However, a suitable target is critical for developing pan-coronavirus antivirals against emerging or re-emerging coronaviruses. In this review, we discuss the latest progress of possible targets of pan-coronavirus antiviral strategies for emerging or re-emerging coronaviruses, including targets for pan-coronavirus inhibitors and vaccines, which will provide prospects for the current and future research and treatment of the disease.
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spelling doaj.art-21e6374d5d7247b9a1e25e65471bd3212023-11-22T04:26:22ZengMDPI AGMicroorganisms2076-26072021-07-0197147910.3390/microorganisms9071479Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging CoronavirusesXue Li0Liying Zhang1Si Chen2Hongsheng Ouyang3Linzhu Ren4Key Laboratory for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, 5333 Xi’An Road, Changchun 130062, ChinaKey Laboratory for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, 5333 Xi’An Road, Changchun 130062, ChinaKey Laboratory for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, 5333 Xi’An Road, Changchun 130062, ChinaKey Laboratory for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, 5333 Xi’An Road, Changchun 130062, ChinaKey Laboratory for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, 5333 Xi’An Road, Changchun 130062, ChinaSevere Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which caused Coronaviruses Disease 2019 (COVID-19) and a worldwide pandemic, is the seventh human coronavirus that has been cross-transmitted from animals to humans. It can be predicted that with continuous contact between humans and animals, more viruses will spread from animals to humans. Therefore, it is imperative to develop universal coronavirus or pan-coronavirus vaccines or drugs against the next coronavirus pandemic. However, a suitable target is critical for developing pan-coronavirus antivirals against emerging or re-emerging coronaviruses. In this review, we discuss the latest progress of possible targets of pan-coronavirus antiviral strategies for emerging or re-emerging coronaviruses, including targets for pan-coronavirus inhibitors and vaccines, which will provide prospects for the current and future research and treatment of the disease.https://www.mdpi.com/2076-2607/9/7/1479pan-coronavirustargetinhibitorvaccineepitope
spellingShingle Xue Li
Liying Zhang
Si Chen
Hongsheng Ouyang
Linzhu Ren
Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses
Microorganisms
pan-coronavirus
target
inhibitor
vaccine
epitope
title Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses
title_full Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses
title_fullStr Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses
title_full_unstemmed Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses
title_short Possible Targets of Pan-Coronavirus Antiviral Strategies for Emerging or Re-Emerging Coronaviruses
title_sort possible targets of pan coronavirus antiviral strategies for emerging or re emerging coronaviruses
topic pan-coronavirus
target
inhibitor
vaccine
epitope
url https://www.mdpi.com/2076-2607/9/7/1479
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