The Effects of Regular Moderate Intensity Exercise on Oxidative Stress and Serum Prolidase Levels: A Comparative Study
Background The effects of exercise on oxidation state is still a controversial topic. Additionally, the relation between exercise and serum levels of prolidase enzyme has not been reported so far. We aim to compare sedentary and physically active individuals regarding the levels of oxidative stress...
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| Format: | Article |
| Language: | English |
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Selcuk University
2021-05-01
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| Series: | Türk Spor ve Egzersiz Dergisi |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/1088242 |
| _version_ | 1797500687781724160 |
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| author | Bülent Güneri Özlem Ekiz Metin Kılınç Adem Doğaner |
| author_facet | Bülent Güneri Özlem Ekiz Metin Kılınç Adem Doğaner |
| author_sort | Bülent Güneri |
| collection | DOAJ |
| description | Background
The effects of exercise on oxidation state is still a controversial topic. Additionally, the relation between exercise and serum levels of prolidase enzyme has not been reported so far. We aim to compare sedentary and physically active individuals regarding the levels of oxidative stress biomarkers and prolidase enzyme.
Materials and Methods
Healthy individuals, 19-22 years old, were enrolled in this study, encompassing the exercise group (n=79) and the sedentary group (n=48). The serum levels of glutathione peroxidase (GPX), catalase, malondialdehyde, total antioxidant status (TAS), total oxidant status (TOS), and prolidase were assayed. Statistical analyses were applied to the findings.
Results
The groups demonstrate insignificant difference regarding the serum GPX (p=0.558) and catalase (p=0.628) levels. The serum levels of malondialdehyde (p lt;0.001) and prolidase (p lt;0.001) are significantly higher in the exercise group and sedentary group than the other group, respectively. The TOS and TAS levels are considerably higher in the exercise group (p=0.025) and sedentary group (p lt;0.001) than the other group, respectively. Statistical analysis demonstrates significant relationship between the prolidase and TAS levels in the exercise group (r=0.243, p=0.031).
Conclusion
The remarkably lower prolidase levels in the exercise group suggest decreased collagen turnover in physically active individuals. Oxidative stress appears to occur without compensation by enzymatic antioxidant mechanisms in young adults, involved in moderate intensity exercises. This study also indicates a correlation between the serum levels of prolidase and TAS in this population. |
| first_indexed | 2024-03-10T03:07:26Z |
| format | Article |
| id | doaj.art-21e85e482efe4d969683ea879e283aa4 |
| institution | Directory Open Access Journal |
| issn | 2147-5652 |
| language | English |
| last_indexed | 2024-03-10T03:07:26Z |
| publishDate | 2021-05-01 |
| publisher | Selcuk University |
| record_format | Article |
| series | Türk Spor ve Egzersiz Dergisi |
| spelling | doaj.art-21e85e482efe4d969683ea879e283aa42023-11-23T10:32:07ZengSelcuk UniversityTürk Spor ve Egzersiz Dergisi2147-56522021-05-01231111118154The Effects of Regular Moderate Intensity Exercise on Oxidative Stress and Serum Prolidase Levels: A Comparative StudyBülent Güneri0Özlem Ekiz1Metin Kılınç2Adem Doğaner3Kahramanmaraş Sütçü İmam University, Faculty of Medicine, Department of Orthopedics and TraumatologyKahramanmaraş Sütçü İmam University, Faculty of Physical Training and SportsKahramanmaraş Sütçü İmam University, Faculty of Medicine, Department of Medical BiochemistryKahramanmaraş Sütçü İmam University, Faculty of Medicine, Department of Biostatistics and Medical InformaticsBackground The effects of exercise on oxidation state is still a controversial topic. Additionally, the relation between exercise and serum levels of prolidase enzyme has not been reported so far. We aim to compare sedentary and physically active individuals regarding the levels of oxidative stress biomarkers and prolidase enzyme. Materials and Methods Healthy individuals, 19-22 years old, were enrolled in this study, encompassing the exercise group (n=79) and the sedentary group (n=48). The serum levels of glutathione peroxidase (GPX), catalase, malondialdehyde, total antioxidant status (TAS), total oxidant status (TOS), and prolidase were assayed. Statistical analyses were applied to the findings. Results The groups demonstrate insignificant difference regarding the serum GPX (p=0.558) and catalase (p=0.628) levels. The serum levels of malondialdehyde (p lt;0.001) and prolidase (p lt;0.001) are significantly higher in the exercise group and sedentary group than the other group, respectively. The TOS and TAS levels are considerably higher in the exercise group (p=0.025) and sedentary group (p lt;0.001) than the other group, respectively. Statistical analysis demonstrates significant relationship between the prolidase and TAS levels in the exercise group (r=0.243, p=0.031). Conclusion The remarkably lower prolidase levels in the exercise group suggest decreased collagen turnover in physically active individuals. Oxidative stress appears to occur without compensation by enzymatic antioxidant mechanisms in young adults, involved in moderate intensity exercises. This study also indicates a correlation between the serum levels of prolidase and TAS in this population.https://dergipark.org.tr/tr/download/article-file/1088242exerciseexopeptidasefree radical scavengersmalondialdehydeoxidative stressegzersizekzopeptidazserbest radikal temizleyicilerimalondialdehitoksidatif stres |
| spellingShingle | Bülent Güneri Özlem Ekiz Metin Kılınç Adem Doğaner The Effects of Regular Moderate Intensity Exercise on Oxidative Stress and Serum Prolidase Levels: A Comparative Study Türk Spor ve Egzersiz Dergisi exercise exopeptidase free radical scavengers malondialdehyde oxidative stress egzersiz ekzopeptidaz serbest radikal temizleyicileri malondialdehit oksidatif stres |
| title | The Effects of Regular Moderate Intensity Exercise on Oxidative Stress and Serum Prolidase Levels: A Comparative Study |
| title_full | The Effects of Regular Moderate Intensity Exercise on Oxidative Stress and Serum Prolidase Levels: A Comparative Study |
| title_fullStr | The Effects of Regular Moderate Intensity Exercise on Oxidative Stress and Serum Prolidase Levels: A Comparative Study |
| title_full_unstemmed | The Effects of Regular Moderate Intensity Exercise on Oxidative Stress and Serum Prolidase Levels: A Comparative Study |
| title_short | The Effects of Regular Moderate Intensity Exercise on Oxidative Stress and Serum Prolidase Levels: A Comparative Study |
| title_sort | effects of regular moderate intensity exercise on oxidative stress and serum prolidase levels a comparative study |
| topic | exercise exopeptidase free radical scavengers malondialdehyde oxidative stress egzersiz ekzopeptidaz serbest radikal temizleyicileri malondialdehit oksidatif stres |
| url | https://dergipark.org.tr/tr/download/article-file/1088242 |
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