Methods of DNa methylation analysis:possibilities and limitations of their application in oncology

Methods of DNa methylation analysis:possibilities and limitations of their application in oncology

Abnormalities of DNA methylation play a significant role in initiation and progression of tumors. In this regard it is necessary to study these aberrations in order to better understand the malignant transformation pathogenesis. For this purpose the adequate and objective methods are required. The p...

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Bibliographic Details
Main Authors: N. A. Skryabin, A. A. Kashevarova, E. V. Denisov, I. N. Lebedev
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2016-02-01
Series:Сибирский онкологический журнал
Subjects:
метилирование днк, бисульфитная модификация, метил-чувствительные рестриктазы, иммунопреципитация метилированной днк, метилочипы
Online Access:https://www.siboncoj.ru/jour/article/view/256

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