Candida auris, an Emerging Fungal Pathogen
The emerging pathogen “Candida auris” is attracting considerable international attention due to its rising reports, transmission through health professionals, high rate of treatment failure and resistance to multiple antifungal agents, particularly fluconazole. In spite of the global emergence of C....
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2019-05-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-12227-en.html |
| _version_ | 1828054910263885824 |
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| author | Shahram Mahmoudi Kazem Ahmadikia Mohammad Kord Ali Ahmadi Sadegh Khodavaisy |
| author_facet | Shahram Mahmoudi Kazem Ahmadikia Mohammad Kord Ali Ahmadi Sadegh Khodavaisy |
| author_sort | Shahram Mahmoudi |
| collection | DOAJ |
| description | The emerging pathogen “Candida auris” is attracting considerable international attention due to its rising reports, transmission through health professionals, high rate of treatment failure and resistance to multiple antifungal agents, particularly fluconazole. In spite of the global emergence of C. auris, epidemiological data and true prevalence of infections due to this organism are not clearly determined due to incapability of conventional and biochemical identification methods. Consequently, this species is erroneously identified as C. haemulonii or Rhodotorula glutinis because of their close phenotypical and biochemical resemblance. Therefore, awareness of serious menace posed by C. auris is of great importance for physicians and health laboratory personnel. This awareness could play a beneficial role in prevention of healthcare-associated outbreaks, timely and definite diagnosis, prompt initiation of C. auris-targeted therapy, and subsequently improving treatment outcomes. This review aimed to discuss the epidemiology, drug resistance, diagnostic challenges, the mode of transmission, and the strategies for prevention of C. auris-related infections. |
| first_indexed | 2024-04-10T20:30:23Z |
| format | Article |
| id | doaj.art-21ec82741ae34d2f8f297d191550c1c3 |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T20:30:23Z |
| publishDate | 2019-05-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-21ec82741ae34d2f8f297d191550c1c32023-01-25T06:57:44ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792019-05-0129172170187Candida auris, an Emerging Fungal PathogenShahram Mahmoudi0Kazem Ahmadikia1Mohammad Kord2Ali Ahmadi3Sadegh Khodavaisy4 PhD Candidate in Medical Mycology, Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran PhD Candidate in Medical Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran PhD Candidate in Medical Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran PhD Candidate in Medical Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran MSc Student in Medical Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Assistant Professor, Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran The emerging pathogen “Candida auris” is attracting considerable international attention due to its rising reports, transmission through health professionals, high rate of treatment failure and resistance to multiple antifungal agents, particularly fluconazole. In spite of the global emergence of C. auris, epidemiological data and true prevalence of infections due to this organism are not clearly determined due to incapability of conventional and biochemical identification methods. Consequently, this species is erroneously identified as C. haemulonii or Rhodotorula glutinis because of their close phenotypical and biochemical resemblance. Therefore, awareness of serious menace posed by C. auris is of great importance for physicians and health laboratory personnel. This awareness could play a beneficial role in prevention of healthcare-associated outbreaks, timely and definite diagnosis, prompt initiation of C. auris-targeted therapy, and subsequently improving treatment outcomes. This review aimed to discuss the epidemiology, drug resistance, diagnostic challenges, the mode of transmission, and the strategies for prevention of C. auris-related infections.http://jmums.mazums.ac.ir/article-1-12227-en.htmlcandida auriscross infectionemerging pathogendrug resistance |
| spellingShingle | Shahram Mahmoudi Kazem Ahmadikia Mohammad Kord Ali Ahmadi Sadegh Khodavaisy Candida auris, an Emerging Fungal Pathogen Journal of Mazandaran University of Medical Sciences candida auris cross infection emerging pathogen drug resistance |
| title | Candida auris, an Emerging Fungal Pathogen |
| title_full | Candida auris, an Emerging Fungal Pathogen |
| title_fullStr | Candida auris, an Emerging Fungal Pathogen |
| title_full_unstemmed | Candida auris, an Emerging Fungal Pathogen |
| title_short | Candida auris, an Emerging Fungal Pathogen |
| title_sort | candida auris an emerging fungal pathogen |
| topic | candida auris cross infection emerging pathogen drug resistance |
| url | http://jmums.mazums.ac.ir/article-1-12227-en.html |
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