Data in support of dyslipidemia-associated alterations in B cell subpopulations frequency and phenotype during experimental atherosclerosis
Cardiovascular diseases are the most common cause of death in the world, atherosclerosis being its main underlying disease. Information about the role of B cells during atherosclerotic process is scarce, but both proatherogenic and atheroprotective properties have been described in the immunopatholo...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2016-06-01
|
| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340916300701 |
| _version_ | 1818309580418973696 |
|---|---|
| author | Héctor Rincón-Arévalo Diana Castaño Janny Villa-Pulgarín Mauricio Rojas Gloria Vásquez Luis A. Correa José R. Ramírez-Pineda Lina M. Yassin |
| author_facet | Héctor Rincón-Arévalo Diana Castaño Janny Villa-Pulgarín Mauricio Rojas Gloria Vásquez Luis A. Correa José R. Ramírez-Pineda Lina M. Yassin |
| author_sort | Héctor Rincón-Arévalo |
| collection | DOAJ |
| description | Cardiovascular diseases are the most common cause of death in the world, atherosclerosis being its main underlying disease. Information about the role of B cells during atherosclerotic process is scarce, but both proatherogenic and atheroprotective properties have been described in the immunopathology of this disease. Frequency and phenotype of B cell subpopulations were studied in wild type and apolipoprotein-E-deficient (apoE−/−) mice fed or not with high-fat diet (HFD), by flow cytometry. Here, we provide the information about the materials, methods, analysis and additional information related to our study published in Atherosclerosis (DOI: 10.1016/j.atherosclerosis.2015.12.022, article reference: ATH14410) [1]. The data contained in this article shows and supports that mice with advanced atherosclerosis have a variety of alterations in frequency and phenotype of B cell subsets, most of which associated with dyslipidemia. Keywords: B cells, Atherosclerosis, Apolipoprotein E, Cholesterol, Dyslipidemia |
| first_indexed | 2024-12-13T07:32:26Z |
| format | Article |
| id | doaj.art-21efb72e28174811b58834838a70de39 |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-13T07:32:26Z |
| publishDate | 2016-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-21efb72e28174811b58834838a70de392022-12-21T23:55:10ZengElsevierData in Brief2352-34092016-06-017958972Data in support of dyslipidemia-associated alterations in B cell subpopulations frequency and phenotype during experimental atherosclerosisHéctor Rincón-Arévalo0Diana Castaño1Janny Villa-Pulgarín2Mauricio Rojas3Gloria Vásquez4Luis A. Correa5José R. Ramírez-Pineda6Lina M. Yassin7Grupo de Inmunología Celular e Inmunogenética, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, ColombiaGrupo de Inmunología Celular e Inmunogenética, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, ColombiaGrupo Inmunomodulación, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, ColombiaGrupo de Inmunología Celular e Inmunogenética, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, Colombia; Unidad de Citometría, Facultad de Medicina, Sede de Investigación Universitaria, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, ColombiaGrupo de Inmunología Celular e Inmunogenética, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, ColombiaSección de Dermatología, Departamento de Medicina Interna, Facultad de Medicina, Universidad de Antioquia. Laboratorio Clínico VID, Obra de la Congregación Mariana, Medellín, ColombiaGrupo Inmunomodulación, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, ColombiaGrupo de Ciencias Básicas, Universidad CES, Medellín, Colombia; Correspondence to. Carrera 53-61-30. Laboratorio 410, Medellín, Colombia. Tel.: +573 3015915008.Cardiovascular diseases are the most common cause of death in the world, atherosclerosis being its main underlying disease. Information about the role of B cells during atherosclerotic process is scarce, but both proatherogenic and atheroprotective properties have been described in the immunopathology of this disease. Frequency and phenotype of B cell subpopulations were studied in wild type and apolipoprotein-E-deficient (apoE−/−) mice fed or not with high-fat diet (HFD), by flow cytometry. Here, we provide the information about the materials, methods, analysis and additional information related to our study published in Atherosclerosis (DOI: 10.1016/j.atherosclerosis.2015.12.022, article reference: ATH14410) [1]. The data contained in this article shows and supports that mice with advanced atherosclerosis have a variety of alterations in frequency and phenotype of B cell subsets, most of which associated with dyslipidemia. Keywords: B cells, Atherosclerosis, Apolipoprotein E, Cholesterol, Dyslipidemiahttp://www.sciencedirect.com/science/article/pii/S2352340916300701 |
| spellingShingle | Héctor Rincón-Arévalo Diana Castaño Janny Villa-Pulgarín Mauricio Rojas Gloria Vásquez Luis A. Correa José R. Ramírez-Pineda Lina M. Yassin Data in support of dyslipidemia-associated alterations in B cell subpopulations frequency and phenotype during experimental atherosclerosis Data in Brief |
| title | Data in support of dyslipidemia-associated alterations in B cell subpopulations frequency and phenotype during experimental atherosclerosis |
| title_full | Data in support of dyslipidemia-associated alterations in B cell subpopulations frequency and phenotype during experimental atherosclerosis |
| title_fullStr | Data in support of dyslipidemia-associated alterations in B cell subpopulations frequency and phenotype during experimental atherosclerosis |
| title_full_unstemmed | Data in support of dyslipidemia-associated alterations in B cell subpopulations frequency and phenotype during experimental atherosclerosis |
| title_short | Data in support of dyslipidemia-associated alterations in B cell subpopulations frequency and phenotype during experimental atherosclerosis |
| title_sort | data in support of dyslipidemia associated alterations in b cell subpopulations frequency and phenotype during experimental atherosclerosis |
| url | http://www.sciencedirect.com/science/article/pii/S2352340916300701 |
| work_keys_str_mv | AT hectorrinconarevalo datainsupportofdyslipidemiaassociatedalterationsinbcellsubpopulationsfrequencyandphenotypeduringexperimentalatherosclerosis AT dianacastano datainsupportofdyslipidemiaassociatedalterationsinbcellsubpopulationsfrequencyandphenotypeduringexperimentalatherosclerosis AT jannyvillapulgarin datainsupportofdyslipidemiaassociatedalterationsinbcellsubpopulationsfrequencyandphenotypeduringexperimentalatherosclerosis AT mauriciorojas datainsupportofdyslipidemiaassociatedalterationsinbcellsubpopulationsfrequencyandphenotypeduringexperimentalatherosclerosis AT gloriavasquez datainsupportofdyslipidemiaassociatedalterationsinbcellsubpopulationsfrequencyandphenotypeduringexperimentalatherosclerosis AT luisacorrea datainsupportofdyslipidemiaassociatedalterationsinbcellsubpopulationsfrequencyandphenotypeduringexperimentalatherosclerosis AT joserramirezpineda datainsupportofdyslipidemiaassociatedalterationsinbcellsubpopulationsfrequencyandphenotypeduringexperimentalatherosclerosis AT linamyassin datainsupportofdyslipidemiaassociatedalterationsinbcellsubpopulationsfrequencyandphenotypeduringexperimentalatherosclerosis |