Aberrant Zip14 expression in muscle is associated with cachexia in a Bard1‐deficient mouse model of breast cancer metastasis

Aberrant Zip14 expression in muscle is associated with cachexia in a Bard1‐deficient mouse model of breast cancer metastasis

Abstract Nearly 80% of advanced cancer patients are afflicted with cachexia, a debilitating syndrome characterized by extensive loss of muscle mass and function. Cachectic cancer patients have a reduced tolerance to antineoplastic therapies and often succumb to premature death from the wasting of re...

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Bibliographic Details
Main Authors: Ahmad Rushdi Shakri, Timothy James Zhong, Wanchao Ma, Courtney Coker, Rohaan Hegde, Hanna Scholze, Vanessa Chin, Matthias Szabolcs, Hanina Hibshoosh, Kurenai Tanji, Richard Baer, Anup Kumar Biswas, Swarnali Acharyya
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Cancer Medicine
Subjects:
BRCA mutations
breast cancer
cachexia
metastasis
mouse models
Online Access:https://doi.org/10.1002/cam4.3242

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