Two-way communication between cell cycle and metabolism in budding yeast: what do we know?
Coordination of cell cycle and metabolism exists in all cells. The building of a new cell is a process that requires metabolic commitment to the provision of both Gibbs energy and building blocks for proteins, nucleic acids, and membranes. On the other hand, the cell cycle machinery will assess and...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-06-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1187304/full |
| _version_ | 1797803779494510592 |
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| author | Yanfei Zhang Yanfei Zhang Lucas van der Zee Matteo Barberis Matteo Barberis Matteo Barberis |
| author_facet | Yanfei Zhang Yanfei Zhang Lucas van der Zee Matteo Barberis Matteo Barberis Matteo Barberis |
| author_sort | Yanfei Zhang |
| collection | DOAJ |
| description | Coordination of cell cycle and metabolism exists in all cells. The building of a new cell is a process that requires metabolic commitment to the provision of both Gibbs energy and building blocks for proteins, nucleic acids, and membranes. On the other hand, the cell cycle machinery will assess and regulate its metabolic environment before it makes decisions on when to enter the next cell cycle phase. Furthermore, more and more evidence demonstrate that the metabolism can be regulated by cell cycle progression, as different biosynthesis pathways are preferentially active in different cell cycle phases. Here, we review the available literature providing a critical overview on how cell cycle and metabolism may be coupled with one other, bidirectionally, in the budding yeast Saccharomyces cerevisiae. |
| first_indexed | 2024-03-13T05:26:10Z |
| format | Article |
| id | doaj.art-21f48baceb5146398809e177c06b947d |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-03-13T05:26:10Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-21f48baceb5146398809e177c06b947d2023-06-15T05:35:41ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2023-06-011410.3389/fmicb.2023.11873041187304Two-way communication between cell cycle and metabolism in budding yeast: what do we know?Yanfei Zhang0Yanfei Zhang1Lucas van der Zee2Matteo Barberis3Matteo Barberis4Matteo Barberis5Molecular Systems Biology, School of Biosciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, United KingdomSynthetic Systems Biology and Nuclear Organization, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, NetherlandsSynthetic Systems Biology and Nuclear Organization, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, NetherlandsMolecular Systems Biology, School of Biosciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, United KingdomSynthetic Systems Biology and Nuclear Organization, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, NetherlandsCentre for Mathematical and Computational Biology, CMCB, University of Surrey, Guildford, Surrey, United KingdomCoordination of cell cycle and metabolism exists in all cells. The building of a new cell is a process that requires metabolic commitment to the provision of both Gibbs energy and building blocks for proteins, nucleic acids, and membranes. On the other hand, the cell cycle machinery will assess and regulate its metabolic environment before it makes decisions on when to enter the next cell cycle phase. Furthermore, more and more evidence demonstrate that the metabolism can be regulated by cell cycle progression, as different biosynthesis pathways are preferentially active in different cell cycle phases. Here, we review the available literature providing a critical overview on how cell cycle and metabolism may be coupled with one other, bidirectionally, in the budding yeast Saccharomyces cerevisiae.https://www.frontiersin.org/articles/10.3389/fmicb.2023.1187304/fullcell cyclemetabolismcyclin-dependent kinasecyclinsmetabolic enzymes |
| spellingShingle | Yanfei Zhang Yanfei Zhang Lucas van der Zee Matteo Barberis Matteo Barberis Matteo Barberis Two-way communication between cell cycle and metabolism in budding yeast: what do we know? Frontiers in Microbiology cell cycle metabolism cyclin-dependent kinase cyclins metabolic enzymes |
| title | Two-way communication between cell cycle and metabolism in budding yeast: what do we know? |
| title_full | Two-way communication between cell cycle and metabolism in budding yeast: what do we know? |
| title_fullStr | Two-way communication between cell cycle and metabolism in budding yeast: what do we know? |
| title_full_unstemmed | Two-way communication between cell cycle and metabolism in budding yeast: what do we know? |
| title_short | Two-way communication between cell cycle and metabolism in budding yeast: what do we know? |
| title_sort | two way communication between cell cycle and metabolism in budding yeast what do we know |
| topic | cell cycle metabolism cyclin-dependent kinase cyclins metabolic enzymes |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1187304/full |
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