Pharmacological potentials of Premna integrifolia L.

Premna integrifolia Linn. (Verbenaceae) is an important constituent of the formulation of ten roots of herbs known as Daśamūla and is widely used for treating various ailments in the Indian system of medicine. Aim of this review is to provide comprehensive information on the pharmacological activiti...

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Main Author: Prashant Y Mali
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Ancient Science of Life
Subjects:
Online Access:http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2016;volume=35;issue=3;spage=132;epage=142;aulast=Mali
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author Prashant Y Mali
author_facet Prashant Y Mali
author_sort Prashant Y Mali
collection DOAJ
description Premna integrifolia Linn. (Verbenaceae) is an important constituent of the formulation of ten roots of herbs known as Daśamūla and is widely used for treating various ailments in the Indian system of medicine. Aim of this review is to provide comprehensive information on the pharmacological activities of various parts of P. integrifolia. All the relevant universally accepted electronic databases were searched with respect to the terms “Agnimanthā”, “Headache tree”, “Premna integrifolia”, “Premna obtusifolia”, “Premna serratifolia” including Indian classical texts, pharmacopoeias, Ayurvedic books, journals, etc., for information without specific timeline. Complete information of the plant has been collected manually since the year 1964 and has been arranged chronologically. The collected data reflects that many ethno-medicinal claims have been confirmed through the modern in-vitro and in-vivo pharmacological studies using different extracts and their isolates of P. integrifolia. The isolation of active constituents, their biological actions, clinical safety and validation of traditional uses of P. integrifolia could provide leads for further scientific research. The information collected here will be useful to set-up research protocols for modern drugs and Ayurvedic formulation development.
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spelling doaj.art-21f4ab99161047a9bcf274b43d0303732022-12-22T03:16:12ZengWolters Kluwer Medknow PublicationsAncient Science of Life0257-79412016-01-0135313214210.4103/0257-7941.179864Pharmacological potentials of Premna integrifolia L.Prashant Y MaliPremna integrifolia Linn. (Verbenaceae) is an important constituent of the formulation of ten roots of herbs known as Daśamūla and is widely used for treating various ailments in the Indian system of medicine. Aim of this review is to provide comprehensive information on the pharmacological activities of various parts of P. integrifolia. All the relevant universally accepted electronic databases were searched with respect to the terms “Agnimanthā”, “Headache tree”, “Premna integrifolia”, “Premna obtusifolia”, “Premna serratifolia” including Indian classical texts, pharmacopoeias, Ayurvedic books, journals, etc., for information without specific timeline. Complete information of the plant has been collected manually since the year 1964 and has been arranged chronologically. The collected data reflects that many ethno-medicinal claims have been confirmed through the modern in-vitro and in-vivo pharmacological studies using different extracts and their isolates of P. integrifolia. The isolation of active constituents, their biological actions, clinical safety and validation of traditional uses of P. integrifolia could provide leads for further scientific research. The information collected here will be useful to set-up research protocols for modern drugs and Ayurvedic formulation development.http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2016;volume=35;issue=3;spage=132;epage=142;aulast=MaliAgnimanthaPremna integrifoliaPremna obtusifoliaPremna serratifoliaare
spellingShingle Prashant Y Mali
Pharmacological potentials of Premna integrifolia L.
Ancient Science of Life
Agnimantha
Premna integrifolia
Premna obtusifolia
Premna serratifoliaare
title Pharmacological potentials of Premna integrifolia L.
title_full Pharmacological potentials of Premna integrifolia L.
title_fullStr Pharmacological potentials of Premna integrifolia L.
title_full_unstemmed Pharmacological potentials of Premna integrifolia L.
title_short Pharmacological potentials of Premna integrifolia L.
title_sort pharmacological potentials of premna integrifolia l
topic Agnimantha
Premna integrifolia
Premna obtusifolia
Premna serratifoliaare
url http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2016;volume=35;issue=3;spage=132;epage=142;aulast=Mali
work_keys_str_mv AT prashantymali pharmacologicalpotentialsofpremnaintegrifolial