The effects of Fc fusion protein glucagon-like peptide-1 and glucagon dual receptor agonist with different receptor selectivity in vivo studies

The effects of Fc fusion protein glucagon-like peptide-1 and glucagon dual receptor agonist with different receptor selectivity in vivo studies

Background: Glucagon-like peptide-1 (GLP-1)/glucagon (GCG) dual receptor agonists with different receptor selectivity are under investigation and have shown significant improvement in both weight loss and glycemic control, but the optimal potency ratio between the two receptors to balance efficacy a...

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Bibliographic Details
Main Authors: Peng Jiang, Ying Zeng, Wen Yang, Lijia Li, Linjun Zhou, Lin Xiao, Yong Li, Baohua Gu, Xiaoping Li, Jing Li, Wenjia Li, Linfeng Guo
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Glucagon
GLP-1
Obesity
MASLD
Weight loss
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222400369X

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