A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome

Sjögren's syndrome is a systemic autoimmune disease characterized by sicca symptoms and extraglandular manifestations. Anemia, leukopenia, thrombocytopenia and lymphoproliferative disorders are well-known extraglandular, hematological complications of Sjögren's syndrome. These hematologic...

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Main Authors: Yeong Seop Yun, Ji Wook Choi, Young Jae Doo, Tae Hyung Kim, Hye Lim Oh, Ji Min Oh
Format: Article
Language:English
Published: Kosin University College of Medicine 2017-06-01
Series:Kosin Medical Journal
Subjects:
Online Access:http://www.kosinmedj.org/upload/pdf/ksmc032-01-13.pdf
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author Yeong Seop Yun
Ji Wook Choi
Young Jae Doo
Tae Hyung Kim
Hye Lim Oh
Ji Min Oh
author_facet Yeong Seop Yun
Ji Wook Choi
Young Jae Doo
Tae Hyung Kim
Hye Lim Oh
Ji Min Oh
author_sort Yeong Seop Yun
collection DOAJ
description Sjögren's syndrome is a systemic autoimmune disease characterized by sicca symptoms and extraglandular manifestations. Anemia, leukopenia, thrombocytopenia and lymphoproliferative disorders are well-known extraglandular, hematological complications of Sjögren's syndrome. These hematologic alterations are usually mild and respond well with steroid therapy. We report a case of a 52-year-old female patient who was initially presented with thrombocytopenia. The patient was then diagnosed with primary Sjögren's syndrome and initially treated with steroid. The patient's platelet count was decreased when steroid was tapered. The dose of steroid could be effectively reduced after combined medication with hydroxychloroquine.
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spelling doaj.art-21f5c1b08ab943ad8024f4ed922e1cb42022-12-22T04:35:10ZengKosin University College of MedicineKosin Medical Journal2005-95312017-06-0132111812610.7180/kmj.2017.32.1.11828A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's SyndromeYeong Seop Yun0Ji Wook Choi1Young Jae Doo2Tae Hyung Kim3Hye Lim Oh4Ji Min Oh5Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea.Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea.Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea.Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea.Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea.Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea.Sjögren's syndrome is a systemic autoimmune disease characterized by sicca symptoms and extraglandular manifestations. Anemia, leukopenia, thrombocytopenia and lymphoproliferative disorders are well-known extraglandular, hematological complications of Sjögren's syndrome. These hematologic alterations are usually mild and respond well with steroid therapy. We report a case of a 52-year-old female patient who was initially presented with thrombocytopenia. The patient was then diagnosed with primary Sjögren's syndrome and initially treated with steroid. The patient's platelet count was decreased when steroid was tapered. The dose of steroid could be effectively reduced after combined medication with hydroxychloroquine.http://www.kosinmedj.org/upload/pdf/ksmc032-01-13.pdfhydroxychloroquineprimary sjögren's syndromesteroidthrombocytopenia
spellingShingle Yeong Seop Yun
Ji Wook Choi
Young Jae Doo
Tae Hyung Kim
Hye Lim Oh
Ji Min Oh
A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome
Kosin Medical Journal
hydroxychloroquine
primary sjögren's syndrome
steroid
thrombocytopenia
title A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome
title_full A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome
title_fullStr A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome
title_full_unstemmed A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome
title_short A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome
title_sort case of treatment with steroid and hydrochloroquine of thrombocytopenia in primary sjogren s syndrome
topic hydroxychloroquine
primary sjögren's syndrome
steroid
thrombocytopenia
url http://www.kosinmedj.org/upload/pdf/ksmc032-01-13.pdf
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