A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome
Sjögren's syndrome is a systemic autoimmune disease characterized by sicca symptoms and extraglandular manifestations. Anemia, leukopenia, thrombocytopenia and lymphoproliferative disorders are well-known extraglandular, hematological complications of Sjögren's syndrome. These hematologic...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Kosin University College of Medicine
2017-06-01
|
Series: | Kosin Medical Journal |
Subjects: | |
Online Access: | http://www.kosinmedj.org/upload/pdf/ksmc032-01-13.pdf |
_version_ | 1797989149642326016 |
---|---|
author | Yeong Seop Yun Ji Wook Choi Young Jae Doo Tae Hyung Kim Hye Lim Oh Ji Min Oh |
author_facet | Yeong Seop Yun Ji Wook Choi Young Jae Doo Tae Hyung Kim Hye Lim Oh Ji Min Oh |
author_sort | Yeong Seop Yun |
collection | DOAJ |
description | Sjögren's syndrome is a systemic autoimmune disease characterized by sicca symptoms and extraglandular manifestations. Anemia, leukopenia, thrombocytopenia and lymphoproliferative disorders are well-known extraglandular, hematological complications of Sjögren's syndrome. These hematologic alterations are usually mild and respond well with steroid therapy. We report a case of a 52-year-old female patient who was initially presented with thrombocytopenia. The patient was then diagnosed with primary Sjögren's syndrome and initially treated with steroid. The patient's platelet count was decreased when steroid was tapered. The dose of steroid could be effectively reduced after combined medication with hydroxychloroquine. |
first_indexed | 2024-04-11T08:15:40Z |
format | Article |
id | doaj.art-21f5c1b08ab943ad8024f4ed922e1cb4 |
institution | Directory Open Access Journal |
issn | 2005-9531 |
language | English |
last_indexed | 2024-04-11T08:15:40Z |
publishDate | 2017-06-01 |
publisher | Kosin University College of Medicine |
record_format | Article |
series | Kosin Medical Journal |
spelling | doaj.art-21f5c1b08ab943ad8024f4ed922e1cb42022-12-22T04:35:10ZengKosin University College of MedicineKosin Medical Journal2005-95312017-06-0132111812610.7180/kmj.2017.32.1.11828A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's SyndromeYeong Seop Yun0Ji Wook Choi1Young Jae Doo2Tae Hyung Kim3Hye Lim Oh4Ji Min Oh5Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea.Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea.Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea.Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea.Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea.Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea.Sjögren's syndrome is a systemic autoimmune disease characterized by sicca symptoms and extraglandular manifestations. Anemia, leukopenia, thrombocytopenia and lymphoproliferative disorders are well-known extraglandular, hematological complications of Sjögren's syndrome. These hematologic alterations are usually mild and respond well with steroid therapy. We report a case of a 52-year-old female patient who was initially presented with thrombocytopenia. The patient was then diagnosed with primary Sjögren's syndrome and initially treated with steroid. The patient's platelet count was decreased when steroid was tapered. The dose of steroid could be effectively reduced after combined medication with hydroxychloroquine.http://www.kosinmedj.org/upload/pdf/ksmc032-01-13.pdfhydroxychloroquineprimary sjögren's syndromesteroidthrombocytopenia |
spellingShingle | Yeong Seop Yun Ji Wook Choi Young Jae Doo Tae Hyung Kim Hye Lim Oh Ji Min Oh A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome Kosin Medical Journal hydroxychloroquine primary sjögren's syndrome steroid thrombocytopenia |
title | A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome |
title_full | A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome |
title_fullStr | A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome |
title_full_unstemmed | A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome |
title_short | A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome |
title_sort | case of treatment with steroid and hydrochloroquine of thrombocytopenia in primary sjogren s syndrome |
topic | hydroxychloroquine primary sjögren's syndrome steroid thrombocytopenia |
url | http://www.kosinmedj.org/upload/pdf/ksmc032-01-13.pdf |
work_keys_str_mv | AT yeongseopyun acaseoftreatmentwithsteroidandhydrochloroquineofthrombocytopeniainprimarysjogrenssyndrome AT jiwookchoi acaseoftreatmentwithsteroidandhydrochloroquineofthrombocytopeniainprimarysjogrenssyndrome AT youngjaedoo acaseoftreatmentwithsteroidandhydrochloroquineofthrombocytopeniainprimarysjogrenssyndrome AT taehyungkim acaseoftreatmentwithsteroidandhydrochloroquineofthrombocytopeniainprimarysjogrenssyndrome AT hyelimoh acaseoftreatmentwithsteroidandhydrochloroquineofthrombocytopeniainprimarysjogrenssyndrome AT jiminoh acaseoftreatmentwithsteroidandhydrochloroquineofthrombocytopeniainprimarysjogrenssyndrome AT yeongseopyun caseoftreatmentwithsteroidandhydrochloroquineofthrombocytopeniainprimarysjogrenssyndrome AT jiwookchoi caseoftreatmentwithsteroidandhydrochloroquineofthrombocytopeniainprimarysjogrenssyndrome AT youngjaedoo caseoftreatmentwithsteroidandhydrochloroquineofthrombocytopeniainprimarysjogrenssyndrome AT taehyungkim caseoftreatmentwithsteroidandhydrochloroquineofthrombocytopeniainprimarysjogrenssyndrome AT hyelimoh caseoftreatmentwithsteroidandhydrochloroquineofthrombocytopeniainprimarysjogrenssyndrome AT jiminoh caseoftreatmentwithsteroidandhydrochloroquineofthrombocytopeniainprimarysjogrenssyndrome |