Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports
Nicola Ughi, Chiara Crotti, Francesca Ingegnoli Division of Rheumatology, Department of Clinical Sciences and Community Health, Gaetano Pini Institute, The University of Milan, Milan, Italy Abstract: Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosi...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2016-03-01
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| Series: | Clinical Interventions in Aging |
| Subjects: | |
| Online Access: | https://www.dovepress.com/effectiveness-and-safety-of-oxycodonenaloxone-in-the-management-of-chr-peer-reviewed-article-CIA |
| _version_ | 1819043999066882048 |
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| author | Ughi N Crotti C Ingegnoli F |
| author_facet | Ughi N Crotti C Ingegnoli F |
| author_sort | Ughi N |
| collection | DOAJ |
| description | Nicola Ughi, Chiara Crotti, Francesca Ingegnoli Division of Rheumatology, Department of Clinical Sciences and Community Health, Gaetano Pini Institute, The University of Milan, Milan, Italy Abstract: Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient’s functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due to pain may be associated with a negative outcome of DU healing. Therefore, pain management has a key role in patients with SSc. These two case reports describe the effectiveness and safety of oxycodone/naloxone in patients with SSc complicated by painful chronic DUs. Such a therapy has provided pain relief and consequently an increased compliance during redressing wounds. Keywords: oxycodone, naloxone, systemic sclerosis, pain, digital ulcer, scleroderma, analgaesia, wound healing, opioids, calcinosis, UCLA-SCTC GIT 2.0 |
| first_indexed | 2024-12-21T10:05:42Z |
| format | Article |
| id | doaj.art-21fb94400327415a9eaf32c4bda4c238 |
| institution | Directory Open Access Journal |
| issn | 1178-1998 |
| language | English |
| last_indexed | 2024-12-21T10:05:42Z |
| publishDate | 2016-03-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Interventions in Aging |
| spelling | doaj.art-21fb94400327415a9eaf32c4bda4c2382022-12-21T19:07:50ZengDove Medical PressClinical Interventions in Aging1178-19982016-03-01Volume 1130731125979Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reportsUghi NCrotti CIngegnoli FNicola Ughi, Chiara Crotti, Francesca Ingegnoli Division of Rheumatology, Department of Clinical Sciences and Community Health, Gaetano Pini Institute, The University of Milan, Milan, Italy Abstract: Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient’s functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due to pain may be associated with a negative outcome of DU healing. Therefore, pain management has a key role in patients with SSc. These two case reports describe the effectiveness and safety of oxycodone/naloxone in patients with SSc complicated by painful chronic DUs. Such a therapy has provided pain relief and consequently an increased compliance during redressing wounds. Keywords: oxycodone, naloxone, systemic sclerosis, pain, digital ulcer, scleroderma, analgaesia, wound healing, opioids, calcinosis, UCLA-SCTC GIT 2.0https://www.dovepress.com/effectiveness-and-safety-of-oxycodonenaloxone-in-the-management-of-chr-peer-reviewed-article-CIAoxycodonenaloxonesystemic sclerosispaindigital ulcersclerodermachronic painopioidscalcinosisUCLA-SCTC GIT 2.0 |
| spellingShingle | Ughi N Crotti C Ingegnoli F Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports Clinical Interventions in Aging oxycodone naloxone systemic sclerosis pain digital ulcer scleroderma chronic pain opioids calcinosis UCLA-SCTC GIT 2.0 |
| title | Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports |
| title_full | Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports |
| title_fullStr | Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports |
| title_full_unstemmed | Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports |
| title_short | Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports |
| title_sort | effectiveness and safety of oxycodone naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers two case reports |
| topic | oxycodone naloxone systemic sclerosis pain digital ulcer scleroderma chronic pain opioids calcinosis UCLA-SCTC GIT 2.0 |
| url | https://www.dovepress.com/effectiveness-and-safety-of-oxycodonenaloxone-in-the-management-of-chr-peer-reviewed-article-CIA |
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