Cementless Ceramic-on-Ceramic Total Hip Replacement in Children and Adolescents

<i>Background</i>: total hip replacement (THR) is a rare surgical option in children and adolescents with disabling hip diseases. The aim of this study is to report results from a retrospective cohort of patients aged 18 years or less who underwent cementless Ceramic-on-Ceramic (CoC) THR...

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Main Authors: Giovanni Trisolino, Stefano Stallone, Francesco Castagnini, Barbara Bordini, Monica Cosentino, Stefano Lucchini, Paola Zarantonello, Daniele Ferrari, Dante Dallari, Francesco Traina
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/8/10/858
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author Giovanni Trisolino
Stefano Stallone
Francesco Castagnini
Barbara Bordini
Monica Cosentino
Stefano Lucchini
Paola Zarantonello
Daniele Ferrari
Dante Dallari
Francesco Traina
author_facet Giovanni Trisolino
Stefano Stallone
Francesco Castagnini
Barbara Bordini
Monica Cosentino
Stefano Lucchini
Paola Zarantonello
Daniele Ferrari
Dante Dallari
Francesco Traina
author_sort Giovanni Trisolino
collection DOAJ
description <i>Background</i>: total hip replacement (THR) is a rare surgical option in children and adolescents with disabling hip diseases. The aim of this study is to report results from a retrospective cohort of patients aged 18 years or less who underwent cementless Ceramic-on-Ceramic (CoC) THR at a single institution, investigating clinical and radiographic outcomes, survival rates, and reasons for revision of the implants. <i>Materials and methods</i>: we queried the Registry of Prosthetic Orthopedic Implants (RIPO) to identify all children and adolescents undergoing THR between 2000 and 2019 at a single Institution. Inclusion criteria were patients undergoing cementless CoC THR, aged less than 18 years at surgery, followed for at least 2 years. Sixty-eight patients (74 hips) matched all the inclusion criteria and were enrolled in the study. We assessed the clinical and radiographic outcomes, the rate of complications, the survival rate, and reasons for revision of the implants. <i>Results</i>: The mean follow-up was 6.6 ± 4.4 years (range 2–20). The most frequent reason for THR was post-traumatic or chemotherapy-induced avascular necrosis (38%). The overall survival rate of the cohort was 97.6% (95% CI: 84.9–99.7%) at 5 years of follow-up, 94.4% (95% CI: 79.8–98.6%) at 10 years and 15 years of follow-up. Two THR in two patients (2.7%) required revision. With the numbers available, Cox regression analysis could not detect any significant interaction between preoperative or intraoperative variables and implant survivorship (<i>p</i>-value 0.242 to 0.989).” The average HOOS was 85 ± 14.3 (range 30.6–100). Overall, 23 patients (48%) reported excellent HOOS scores (>90 points), 21 patients (44%) reported acceptable HOOS scores (60–90 points) while 4 patients (8%) reported poor outcomes (<60 points). Twenty-one patients (43%) were regularly involved into moderate- to high-intensity sport activities (UCLA ≥ 6). <i>Conclusions</i>: Cementless CoC THR is a successful procedure in children and teenagers, having demonstrated high implant survivorship and low rates of complications and failure. A meticulous preoperative planning and implant selection is mandatory, to avoid implant malposition, which is the main reason of failure and revision in these cases. Further studies are needed to assess the impact of the THR on the psychosocial wellbeing of teenagers, as well as risks and benefits and cost-effectiveness in comparison to the hip preserving surgical procedures.
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spelling doaj.art-21fd604875b54161b9f81b25ff62abdb2023-11-22T17:50:13ZengMDPI AGChildren2227-90672021-09-0181085810.3390/children8100858Cementless Ceramic-on-Ceramic Total Hip Replacement in Children and AdolescentsGiovanni Trisolino0Stefano Stallone1Francesco Castagnini2Barbara Bordini3Monica Cosentino4Stefano Lucchini5Paola Zarantonello6Daniele Ferrari7Dante Dallari8Francesco Traina9Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyPediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyOrthopaedic-Traumatology and Prosthetic Surgery and Revisions of Hip and Knee, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyMedical Technology Laboratory, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyMedical Technology Laboratory, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyOrthopaedic-Traumatology and Prosthetic Surgery and Revisions of Hip and Knee, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyPediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyPediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyConservative Orthopedic Surgery and Innovative Techniques, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyOrthopaedic-Traumatology and Prosthetic Surgery and Revisions of Hip and Knee, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy<i>Background</i>: total hip replacement (THR) is a rare surgical option in children and adolescents with disabling hip diseases. The aim of this study is to report results from a retrospective cohort of patients aged 18 years or less who underwent cementless Ceramic-on-Ceramic (CoC) THR at a single institution, investigating clinical and radiographic outcomes, survival rates, and reasons for revision of the implants. <i>Materials and methods</i>: we queried the Registry of Prosthetic Orthopedic Implants (RIPO) to identify all children and adolescents undergoing THR between 2000 and 2019 at a single Institution. Inclusion criteria were patients undergoing cementless CoC THR, aged less than 18 years at surgery, followed for at least 2 years. Sixty-eight patients (74 hips) matched all the inclusion criteria and were enrolled in the study. We assessed the clinical and radiographic outcomes, the rate of complications, the survival rate, and reasons for revision of the implants. <i>Results</i>: The mean follow-up was 6.6 ± 4.4 years (range 2–20). The most frequent reason for THR was post-traumatic or chemotherapy-induced avascular necrosis (38%). The overall survival rate of the cohort was 97.6% (95% CI: 84.9–99.7%) at 5 years of follow-up, 94.4% (95% CI: 79.8–98.6%) at 10 years and 15 years of follow-up. Two THR in two patients (2.7%) required revision. With the numbers available, Cox regression analysis could not detect any significant interaction between preoperative or intraoperative variables and implant survivorship (<i>p</i>-value 0.242 to 0.989).” The average HOOS was 85 ± 14.3 (range 30.6–100). Overall, 23 patients (48%) reported excellent HOOS scores (>90 points), 21 patients (44%) reported acceptable HOOS scores (60–90 points) while 4 patients (8%) reported poor outcomes (<60 points). Twenty-one patients (43%) were regularly involved into moderate- to high-intensity sport activities (UCLA ≥ 6). <i>Conclusions</i>: Cementless CoC THR is a successful procedure in children and teenagers, having demonstrated high implant survivorship and low rates of complications and failure. A meticulous preoperative planning and implant selection is mandatory, to avoid implant malposition, which is the main reason of failure and revision in these cases. Further studies are needed to assess the impact of the THR on the psychosocial wellbeing of teenagers, as well as risks and benefits and cost-effectiveness in comparison to the hip preserving surgical procedures.https://www.mdpi.com/2227-9067/8/10/858arthroplastyreplacementhipchildadolescentceramics
spellingShingle Giovanni Trisolino
Stefano Stallone
Francesco Castagnini
Barbara Bordini
Monica Cosentino
Stefano Lucchini
Paola Zarantonello
Daniele Ferrari
Dante Dallari
Francesco Traina
Cementless Ceramic-on-Ceramic Total Hip Replacement in Children and Adolescents
Children
arthroplasty
replacement
hip
child
adolescent
ceramics
title Cementless Ceramic-on-Ceramic Total Hip Replacement in Children and Adolescents
title_full Cementless Ceramic-on-Ceramic Total Hip Replacement in Children and Adolescents
title_fullStr Cementless Ceramic-on-Ceramic Total Hip Replacement in Children and Adolescents
title_full_unstemmed Cementless Ceramic-on-Ceramic Total Hip Replacement in Children and Adolescents
title_short Cementless Ceramic-on-Ceramic Total Hip Replacement in Children and Adolescents
title_sort cementless ceramic on ceramic total hip replacement in children and adolescents
topic arthroplasty
replacement
hip
child
adolescent
ceramics
url https://www.mdpi.com/2227-9067/8/10/858
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AT barbarabordini cementlessceramiconceramictotalhipreplacementinchildrenandadolescents
AT monicacosentino cementlessceramiconceramictotalhipreplacementinchildrenandadolescents
AT stefanolucchini cementlessceramiconceramictotalhipreplacementinchildrenandadolescents
AT paolazarantonello cementlessceramiconceramictotalhipreplacementinchildrenandadolescents
AT danieleferrari cementlessceramiconceramictotalhipreplacementinchildrenandadolescents
AT dantedallari cementlessceramiconceramictotalhipreplacementinchildrenandadolescents
AT francescotraina cementlessceramiconceramictotalhipreplacementinchildrenandadolescents