CANAKINUMAB IN THE TREATMENT OF RHEUMATIC DISEASES IN CHILDREN
The article describes international multicenter controlled studies of efficacy and safety of monoclonal antibodies towards interleukin 1β — kanakinumab — when treating cryopyrin-associated periodic syndrome and systemic juvenile idiopathic arthritis in children. The results of the studies show that...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2014-12-01
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| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/95 |
| _version_ | 1797700425819881472 |
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| author | Ye. I. Alekseeva R. V. Denisova |
| author_facet | Ye. I. Alekseeva R. V. Denisova |
| author_sort | Ye. I. Alekseeva |
| collection | DOAJ |
| description | The article describes international multicenter controlled studies of efficacy and safety of monoclonal antibodies towards interleukin 1β — kanakinumab — when treating cryopyrin-associated periodic syndrome and systemic juvenile idiopathic arthritis in children. The results of the studies show that the remission of the disease occurred in 90% of patients with cryopyrin-associated periodic syndrome and in 40% of patients with systemic juvenile idiopathic arthritis. The safety profile was comparable to that of other biological agents. |
| first_indexed | 2024-03-12T04:21:44Z |
| format | Article |
| id | doaj.art-21ffc31d284c4ee4a672ad52e3c154b4 |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2024-03-12T04:21:44Z |
| publishDate | 2014-12-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-21ffc31d284c4ee4a672ad52e3c154b42023-09-03T10:32:54Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352014-12-0113691410.15690/vsp.v13i6.119595CANAKINUMAB IN THE TREATMENT OF RHEUMATIC DISEASES IN CHILDRENYe. I. Alekseeva0R. V. Denisova1Научный центр здоровья детей, Москва;, Первый Московский государственный медицинский университет им. И.М. СеченоваНаучный центр здоровья детей, МоскваThe article describes international multicenter controlled studies of efficacy and safety of monoclonal antibodies towards interleukin 1β — kanakinumab — when treating cryopyrin-associated periodic syndrome and systemic juvenile idiopathic arthritis in children. The results of the studies show that the remission of the disease occurred in 90% of patients with cryopyrin-associated periodic syndrome and in 40% of patients with systemic juvenile idiopathic arthritis. The safety profile was comparable to that of other biological agents.https://vsp.spr-journal.ru/jour/article/view/95детиканакинумабсистемный ювенильный идиопатический артриткриопиринассоциированные периодические синдромы |
| spellingShingle | Ye. I. Alekseeva R. V. Denisova CANAKINUMAB IN THE TREATMENT OF RHEUMATIC DISEASES IN CHILDREN Вопросы современной педиатрии дети канакинумаб системный ювенильный идиопатический артрит криопиринассоциированные периодические синдромы |
| title | CANAKINUMAB IN THE TREATMENT OF RHEUMATIC DISEASES IN CHILDREN |
| title_full | CANAKINUMAB IN THE TREATMENT OF RHEUMATIC DISEASES IN CHILDREN |
| title_fullStr | CANAKINUMAB IN THE TREATMENT OF RHEUMATIC DISEASES IN CHILDREN |
| title_full_unstemmed | CANAKINUMAB IN THE TREATMENT OF RHEUMATIC DISEASES IN CHILDREN |
| title_short | CANAKINUMAB IN THE TREATMENT OF RHEUMATIC DISEASES IN CHILDREN |
| title_sort | canakinumab in the treatment of rheumatic diseases in children |
| topic | дети канакинумаб системный ювенильный идиопатический артрит криопиринассоциированные периодические синдромы |
| url | https://vsp.spr-journal.ru/jour/article/view/95 |
| work_keys_str_mv | AT yeialekseeva canakinumabinthetreatmentofrheumaticdiseasesinchildren AT rvdenisova canakinumabinthetreatmentofrheumaticdiseasesinchildren |