Vitamins and carotenoids in the dynamics of prostate gland oncogenesis
The content of vitamins and relative biologically active substances including the products of lipids peroxidation has been studied in the blood of 115 males -patients of Department of Urology of I.M.Sechenov First Moscow State Medical University. The patients have been divided to four groups: prosta...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
2022-12-01
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| Series: | Сеченовский вестник |
| Subjects: | |
| Online Access: | https://www.sechenovmedj.com/jour/article/view/680 |
| _version_ | 1826572242300960768 |
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| author | P. V. Glybochko E. G. Zezerov Yu. G. Alyaev V. B. Spirichev D. V. Butnaru S. E. Severin A. Z. Vinarov N. A. Beketova O. G. Pereverzeva V. A. Varshavsky E. V. Osipov E. A. Bezrukov |
| author_facet | P. V. Glybochko E. G. Zezerov Yu. G. Alyaev V. B. Spirichev D. V. Butnaru S. E. Severin A. Z. Vinarov N. A. Beketova O. G. Pereverzeva V. A. Varshavsky E. V. Osipov E. A. Bezrukov |
| author_sort | P. V. Glybochko |
| collection | DOAJ |
| description | The content of vitamins and relative biologically active substances including the products of lipids peroxidation has been studied in the blood of 115 males -patients of Department of Urology of I.M.Sechenov First Moscow State Medical University. The patients have been divided to four groups: prostatic carcinoma (PC); high grade prostatic intraepithelial neoplasia (HG PIN) or precancer; mixed group of conditional control – low grade PIN, benign prostatic hyperplasia, chronic prostatitis or their combination; control group of healthy men without prostate pathology. Further statistically reliable differences have been found: patients with PC had lower level of antioxidants – lycopene, vitamin E and enhanced level of diene conjugates (products of lipid peroxidation); patients with HG PIN low level of vitamin C, total carotenoids and increased diene conjugates. The difference in vitamins-antioxidants levels in patients with PC and HG PIN has not been found out. |
| first_indexed | 2024-04-10T01:18:11Z |
| format | Article |
| id | doaj.art-220139a10667485a918b0fd31fc9eb65 |
| institution | Directory Open Access Journal |
| issn | 2218-7332 2658-3348 |
| language | Russian |
| last_indexed | 2025-03-14T12:23:54Z |
| publishDate | 2022-12-01 |
| publisher | Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) |
| record_format | Article |
| series | Сеченовский вестник |
| spelling | doaj.art-220139a10667485a918b0fd31fc9eb652025-03-02T09:29:58ZrusFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)Сеченовский вестник2218-73322658-33482022-12-0103-4413374Vitamins and carotenoids in the dynamics of prostate gland oncogenesisP. V. Glybochko0E. G. Zezerov1Yu. G. Alyaev2V. B. Spirichev3D. V. Butnaru4S. E. Severin5A. Z. Vinarov6N. A. Beketova7O. G. Pereverzeva8V. A. Varshavsky9E. V. Osipov10E. A. Bezrukov11First MSMU named after I. M. SechenovFirst MSMU named after I. M. SechenovResearch centre of uronephrology and reproductive health; First MSMU named after I. M. SechenovNutrition Research Institute of RAMSFirst MSMU named after I. M. SechenovFirst MSMU named after I. M. SechenovResearch centre of uronephrology and reproductive health; First MSMU named after I. M. SechenovNutrition Research Institute of RAMSNutrition Research Institute of RAMSFirst MSMU named after I. M. SechenovFirst MSMU named after I. M. SechenovFirst MSMU named after I. M. SechenovThe content of vitamins and relative biologically active substances including the products of lipids peroxidation has been studied in the blood of 115 males -patients of Department of Urology of I.M.Sechenov First Moscow State Medical University. The patients have been divided to four groups: prostatic carcinoma (PC); high grade prostatic intraepithelial neoplasia (HG PIN) or precancer; mixed group of conditional control – low grade PIN, benign prostatic hyperplasia, chronic prostatitis or their combination; control group of healthy men without prostate pathology. Further statistically reliable differences have been found: patients with PC had lower level of antioxidants – lycopene, vitamin E and enhanced level of diene conjugates (products of lipid peroxidation); patients with HG PIN low level of vitamin C, total carotenoids and increased diene conjugates. The difference in vitamins-antioxidants levels in patients with PC and HG PIN has not been found out.https://www.sechenovmedj.com/jour/article/view/680prostate cancerprecancerprostatic intraepithelial neoplasiavitaminscarotenoidslycopenebeta-caroteneblood serum |
| spellingShingle | P. V. Glybochko E. G. Zezerov Yu. G. Alyaev V. B. Spirichev D. V. Butnaru S. E. Severin A. Z. Vinarov N. A. Beketova O. G. Pereverzeva V. A. Varshavsky E. V. Osipov E. A. Bezrukov Vitamins and carotenoids in the dynamics of prostate gland oncogenesis Сеченовский вестник prostate cancer precancer prostatic intraepithelial neoplasia vitamins carotenoids lycopene beta-carotene blood serum |
| title | Vitamins and carotenoids in the dynamics of prostate gland oncogenesis |
| title_full | Vitamins and carotenoids in the dynamics of prostate gland oncogenesis |
| title_fullStr | Vitamins and carotenoids in the dynamics of prostate gland oncogenesis |
| title_full_unstemmed | Vitamins and carotenoids in the dynamics of prostate gland oncogenesis |
| title_short | Vitamins and carotenoids in the dynamics of prostate gland oncogenesis |
| title_sort | vitamins and carotenoids in the dynamics of prostate gland oncogenesis |
| topic | prostate cancer precancer prostatic intraepithelial neoplasia vitamins carotenoids lycopene beta-carotene blood serum |
| url | https://www.sechenovmedj.com/jour/article/view/680 |
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