Enhanced disinfection with hybrid hydrogen peroxide fogging in a critical care setting
Abstract Background Environmental contamination contributes to hospital associated infections, particularly those caused by multi-drug resistant organisms (MDRO). This study investigated bioburden presence on surfaces in a critical care center’s patient rooms following typical environmental services...
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| Format: | Article |
| Language: | English |
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BMC
2022-09-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-022-07704-9 |
| _version_ | 1811201002455433216 |
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| author | Anjay Khandelwal Brian Lapolla Tina Bair Frances Grinstead Meaghan Hislop Christine Greene Michael T. Bigham |
| author_facet | Anjay Khandelwal Brian Lapolla Tina Bair Frances Grinstead Meaghan Hislop Christine Greene Michael T. Bigham |
| author_sort | Anjay Khandelwal |
| collection | DOAJ |
| description | Abstract Background Environmental contamination contributes to hospital associated infections, particularly those caused by multi-drug resistant organisms (MDRO). This study investigated bioburden presence on surfaces in a critical care center’s patient rooms following typical environmental services (EVS) practices and following intervention with hybrid hydrogen peroxide™ (HHP™) fogging. Methods Upon patient discharge, following standard cleaning or cleaning with ultraviolet (UV) light use, patient rooms were sampled by swabbing for adenosine triphosphate (ATP) and aerobic colony counts (ACC) from five preset locations. Rooms were then fogged via HHP technology using chemical indicators and Geobacillus stearothermophilus biological indicators for sporicidal validation monitoring. Following fogging, rooms were sampled again, and results were compared. Results A 98% reduction in ACC was observed after fogging as compared to post EVS practices both with and without UV light use. No statistical difference was seen when comparing cleaning to cleaning with UV light use. Methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa were identified following EVS practices and not detected following HHP fogging. ATP samples were reduced 88% by fogging application. Chemical and biological indicators confirmed correct application of HHP fogging, as seen through its achievement of a 6-log reduction of bacterial spores. Conclusion HHP fogging is a thorough and efficacious technology which, when applied to critical care patient rooms, significantly reduces bioburden on surfaces, indicating potential benefits for implementation as part of infection prevention measures. |
| first_indexed | 2024-04-12T02:14:20Z |
| format | Article |
| id | doaj.art-22036f444920438d956733a63655241e |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-04-12T02:14:20Z |
| publishDate | 2022-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-22036f444920438d956733a63655241e2022-12-22T03:52:18ZengBMCBMC Infectious Diseases1471-23342022-09-012211810.1186/s12879-022-07704-9Enhanced disinfection with hybrid hydrogen peroxide fogging in a critical care settingAnjay Khandelwal0Brian Lapolla1Tina Bair2Frances Grinstead3Meaghan Hislop4Christine Greene5Michael T. Bigham6Department of Surgery, Division of Burn Surgery, Paul and Carol David Foundation Burn Institute, Akron Children’s HospitalDepartment of Construction, Facilities and Public Safety, Akron Children’s HospitalDepartment of Infection Prevention and Control, Akron Children’s HospitalDepartment of Executive Management, CURIS SystemDepartment of Scientific Research, CURIS SystemRamboll Group, Ramboll USA, Inc.Department of Quality Services and Division of Pediatric Critical Care, Department of Pediatrics, Akron Children’s HospitalAbstract Background Environmental contamination contributes to hospital associated infections, particularly those caused by multi-drug resistant organisms (MDRO). This study investigated bioburden presence on surfaces in a critical care center’s patient rooms following typical environmental services (EVS) practices and following intervention with hybrid hydrogen peroxide™ (HHP™) fogging. Methods Upon patient discharge, following standard cleaning or cleaning with ultraviolet (UV) light use, patient rooms were sampled by swabbing for adenosine triphosphate (ATP) and aerobic colony counts (ACC) from five preset locations. Rooms were then fogged via HHP technology using chemical indicators and Geobacillus stearothermophilus biological indicators for sporicidal validation monitoring. Following fogging, rooms were sampled again, and results were compared. Results A 98% reduction in ACC was observed after fogging as compared to post EVS practices both with and without UV light use. No statistical difference was seen when comparing cleaning to cleaning with UV light use. Methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa were identified following EVS practices and not detected following HHP fogging. ATP samples were reduced 88% by fogging application. Chemical and biological indicators confirmed correct application of HHP fogging, as seen through its achievement of a 6-log reduction of bacterial spores. Conclusion HHP fogging is a thorough and efficacious technology which, when applied to critical care patient rooms, significantly reduces bioburden on surfaces, indicating potential benefits for implementation as part of infection prevention measures.https://doi.org/10.1186/s12879-022-07704-9Infection preventionDisinfectionHydrogen peroxideHospital-acquired infectionBurnCritical care |
| spellingShingle | Anjay Khandelwal Brian Lapolla Tina Bair Frances Grinstead Meaghan Hislop Christine Greene Michael T. Bigham Enhanced disinfection with hybrid hydrogen peroxide fogging in a critical care setting BMC Infectious Diseases Infection prevention Disinfection Hydrogen peroxide Hospital-acquired infection Burn Critical care |
| title | Enhanced disinfection with hybrid hydrogen peroxide fogging in a critical care setting |
| title_full | Enhanced disinfection with hybrid hydrogen peroxide fogging in a critical care setting |
| title_fullStr | Enhanced disinfection with hybrid hydrogen peroxide fogging in a critical care setting |
| title_full_unstemmed | Enhanced disinfection with hybrid hydrogen peroxide fogging in a critical care setting |
| title_short | Enhanced disinfection with hybrid hydrogen peroxide fogging in a critical care setting |
| title_sort | enhanced disinfection with hybrid hydrogen peroxide fogging in a critical care setting |
| topic | Infection prevention Disinfection Hydrogen peroxide Hospital-acquired infection Burn Critical care |
| url | https://doi.org/10.1186/s12879-022-07704-9 |
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