Electrocardiogram abnormalities and prognosis in COVID-19
BackgroundCOVID-19 is a major pandemic with potential cardiovascular complications. Few studies have focused on electrocardiogram (ECG) modifications in COVID-19 patients.Method and resultsWe reviewed from our database all patients referred to our hospital for COVID-19 between January 1st, 2020, and...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.993479/full |
| _version_ | 1811199114473373696 |
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| author | Gabriel Chevrot Marie Hauguel-Moreau Marie Hauguel-Moreau Marion Pépin Marion Pépin Antoine Vieillard-Baron Antoine Vieillard-Baron Antoine Vieillard-Baron Anne-Sophie Lot Mounir Ouadahi Hélène Hergault Vincent Aïdan Ségolène Greffe Adrien Costantini Olivier Dubourg Olivier Dubourg Sébastien Beaune Sébastien Beaune Nicolas Mansencal Nicolas Mansencal |
| author_facet | Gabriel Chevrot Marie Hauguel-Moreau Marie Hauguel-Moreau Marion Pépin Marion Pépin Antoine Vieillard-Baron Antoine Vieillard-Baron Antoine Vieillard-Baron Anne-Sophie Lot Mounir Ouadahi Hélène Hergault Vincent Aïdan Ségolène Greffe Adrien Costantini Olivier Dubourg Olivier Dubourg Sébastien Beaune Sébastien Beaune Nicolas Mansencal Nicolas Mansencal |
| author_sort | Gabriel Chevrot |
| collection | DOAJ |
| description | BackgroundCOVID-19 is a major pandemic with potential cardiovascular complications. Few studies have focused on electrocardiogram (ECG) modifications in COVID-19 patients.Method and resultsWe reviewed from our database all patients referred to our hospital for COVID-19 between January 1st, 2020, and December 31st, 2020: 669 patients were included and 98 patients died from COVID-19 (14.6%). We systematically analyzed ECG at admission and during hospitalization if available. ECG was abnormal at admission in 478 patients (71.4%) and was more frequently abnormal in patients who did not survive (88.8 vs. 68.5%, p < 0.001). The most common ECG abnormalities associated with death were left anterior fascicular block (39.8 vs. 20.0% among alive patients, p < 0.001), left and right bundle branch blocks (p = 0.002 and p = 0.02, respectively), S1Q3 pattern (14.3 vs. 6.0%, p = 0.006). In multivariate analysis, at admission, the presence of left bundle branch block remained statistically related to death [OR = 3.82, 95% confidence interval (CI): 1.52–9.28, p < 0.01], as well as S1Q3 pattern (OR = 3.17, 95% CI: 1.38–7.03, p < 0.01) and repolarization abnormalities (OR = 2.41, 95% CI: 1.40–4.14, p < 0.01).On ECG performed during hospitalization, the occurrence of new repolarization abnormality was significantly related to death (OR = 2.72, 95% CI: 1.14–6.54, p = 0.02), as well as a new S1Q3 pattern (OR = 13.23, 95% CI: 1.49–286.56, p = 0.03) and new supraventricular arrhythmia (OR = 3.8, 95% CI: 1.11–13.35, p = 0.03).ConclusionThe presence of abnormal ECG during COVID-19 is frequent. Physicians should be aware of the usefulness of ECG for risk stratification during COVID-19. |
| first_indexed | 2024-04-12T01:42:31Z |
| format | Article |
| id | doaj.art-22091507465645d5b8ff5bcdbbb5a1ce |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-12T01:42:31Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-22091507465645d5b8ff5bcdbbb5a1ce2022-12-22T03:53:10ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-10-01910.3389/fcvm.2022.993479993479Electrocardiogram abnormalities and prognosis in COVID-19Gabriel Chevrot0Marie Hauguel-Moreau1Marie Hauguel-Moreau2Marion Pépin3Marion Pépin4Antoine Vieillard-Baron5Antoine Vieillard-Baron6Antoine Vieillard-Baron7Anne-Sophie Lot8Mounir Ouadahi9Hélène Hergault10Vincent Aïdan11Ségolène Greffe12Adrien Costantini13Olivier Dubourg14Olivier Dubourg15Sébastien Beaune16Sébastien Beaune17Nicolas Mansencal18Nicolas Mansencal19Department of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de référence des cardiomyopathies et des troubles du rythme cardiaque héréditaires ou rares, Université de Versailles-Saint Quentin (UVSQ), Boulogne-Billancourt, FranceDepartment of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de référence des cardiomyopathies et des troubles du rythme cardiaque héréditaires ou rares, Université de Versailles-Saint Quentin (UVSQ), Boulogne-Billancourt, FranceINSERM U-1018, CESP, Epidémiologie clinique, UVSQ, Université de Paris Saclay, Villejuif, FranceINSERM U-1018, CESP, Epidémiologie clinique, UVSQ, Université de Paris Saclay, Villejuif, FranceDepartment of Geriatrics, Ambroise Paré Hospital, AP-HP, UVSQ, Boulogne-Billancourt, FranceINSERM U-1018, CESP, Epidémiologie clinique, UVSQ, Université de Paris Saclay, Villejuif, FranceIntensive Care Unit, Ambroise Paré Hospital, AP-HP, UVSQ, Boulogne-Billancourt, FranceFHU SEPSIS IFrancenserm UMR 1144, Université Paris Centre, Paris, FranceDepartment of Medical Information, Ambroise Paré Hospital, APHP, Boulogne-Billancourt, FranceDepartment of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de référence des cardiomyopathies et des troubles du rythme cardiaque héréditaires ou rares, Université de Versailles-Saint Quentin (UVSQ), Boulogne-Billancourt, FranceDepartment of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de référence des cardiomyopathies et des troubles du rythme cardiaque héréditaires ou rares, Université de Versailles-Saint Quentin (UVSQ), Boulogne-Billancourt, FranceDepartment of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de référence des cardiomyopathies et des troubles du rythme cardiaque héréditaires ou rares, Université de Versailles-Saint Quentin (UVSQ), Boulogne-Billancourt, FranceDepartment of Internal Medicine, Ambroise Paré University Hospital, AP-HP, UVSQ, Boulogne-Billancourt, FrancePneumology Department, Ambroise Paré Hospital, AP-HP, UVSQ, Boulogne-Billancourt, FranceDepartment of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de référence des cardiomyopathies et des troubles du rythme cardiaque héréditaires ou rares, Université de Versailles-Saint Quentin (UVSQ), Boulogne-Billancourt, FranceINSERM U-1018, CESP, Epidémiologie clinique, UVSQ, Université de Paris Saclay, Villejuif, FranceFHU SEPSIS IFrancenserm UMR 1144, Université Paris Centre, Paris, FranceDepartment of Emergency Medicine, Ambroise Paré Hospital, AP-HP, UVSQ, Boulogne-Billancourt, FranceDepartment of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de référence des cardiomyopathies et des troubles du rythme cardiaque héréditaires ou rares, Université de Versailles-Saint Quentin (UVSQ), Boulogne-Billancourt, FranceINSERM U-1018, CESP, Epidémiologie clinique, UVSQ, Université de Paris Saclay, Villejuif, FranceBackgroundCOVID-19 is a major pandemic with potential cardiovascular complications. Few studies have focused on electrocardiogram (ECG) modifications in COVID-19 patients.Method and resultsWe reviewed from our database all patients referred to our hospital for COVID-19 between January 1st, 2020, and December 31st, 2020: 669 patients were included and 98 patients died from COVID-19 (14.6%). We systematically analyzed ECG at admission and during hospitalization if available. ECG was abnormal at admission in 478 patients (71.4%) and was more frequently abnormal in patients who did not survive (88.8 vs. 68.5%, p < 0.001). The most common ECG abnormalities associated with death were left anterior fascicular block (39.8 vs. 20.0% among alive patients, p < 0.001), left and right bundle branch blocks (p = 0.002 and p = 0.02, respectively), S1Q3 pattern (14.3 vs. 6.0%, p = 0.006). In multivariate analysis, at admission, the presence of left bundle branch block remained statistically related to death [OR = 3.82, 95% confidence interval (CI): 1.52–9.28, p < 0.01], as well as S1Q3 pattern (OR = 3.17, 95% CI: 1.38–7.03, p < 0.01) and repolarization abnormalities (OR = 2.41, 95% CI: 1.40–4.14, p < 0.01).On ECG performed during hospitalization, the occurrence of new repolarization abnormality was significantly related to death (OR = 2.72, 95% CI: 1.14–6.54, p = 0.02), as well as a new S1Q3 pattern (OR = 13.23, 95% CI: 1.49–286.56, p = 0.03) and new supraventricular arrhythmia (OR = 3.8, 95% CI: 1.11–13.35, p = 0.03).ConclusionThe presence of abnormal ECG during COVID-19 is frequent. Physicians should be aware of the usefulness of ECG for risk stratification during COVID-19.https://www.frontiersin.org/articles/10.3389/fcvm.2022.993479/fullECGCOVID-19prognosisSARS-CoV-2repolarization |
| spellingShingle | Gabriel Chevrot Marie Hauguel-Moreau Marie Hauguel-Moreau Marion Pépin Marion Pépin Antoine Vieillard-Baron Antoine Vieillard-Baron Antoine Vieillard-Baron Anne-Sophie Lot Mounir Ouadahi Hélène Hergault Vincent Aïdan Ségolène Greffe Adrien Costantini Olivier Dubourg Olivier Dubourg Sébastien Beaune Sébastien Beaune Nicolas Mansencal Nicolas Mansencal Electrocardiogram abnormalities and prognosis in COVID-19 Frontiers in Cardiovascular Medicine ECG COVID-19 prognosis SARS-CoV-2 repolarization |
| title | Electrocardiogram abnormalities and prognosis in COVID-19 |
| title_full | Electrocardiogram abnormalities and prognosis in COVID-19 |
| title_fullStr | Electrocardiogram abnormalities and prognosis in COVID-19 |
| title_full_unstemmed | Electrocardiogram abnormalities and prognosis in COVID-19 |
| title_short | Electrocardiogram abnormalities and prognosis in COVID-19 |
| title_sort | electrocardiogram abnormalities and prognosis in covid 19 |
| topic | ECG COVID-19 prognosis SARS-CoV-2 repolarization |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.993479/full |
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