Target inhibition of caspase-8 alleviates brain damage after subarachnoid hemorrhage

Target inhibition of caspase-8 alleviates brain damage after subarachnoid hemorrhage

Caspase-8 plays an important role in the mediation of inflammation and the effect of its role in subarachnoid hemorrhage remains elusive. The nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome has been postulated to mediate inflammation during SAH. The aim of the present...

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Bibliographic Details
Main Authors: Da-Qiang Ke, Zhi-Yang Chen, Zhou-Ling Li, Xia Huang, Hui Liang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
brain water content; caspase-8; inflammation; morris water maze; neurological function; neuroprotection; pyrin domain-containing 3; rotarod test; subarachnoid hemorrhage; z-ietd-fmk
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=7;spage=1283;epage=1289;aulast=Ke

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