Multi-tyrosine kinase inhibitors in preclinical studies for pediatric CNS AT/RT: Evidence for synergy with Topoisomerase-I inhibition

Multi-tyrosine kinase inhibitors in preclinical studies for pediatric CNS AT/RT: Evidence for synergy with Topoisomerase-I inhibition

<p>Abstract</p> <p>Background</p> <p>Currently, Atypical Teratoid Rhabdoid Tumor (AT/RT) constitutes one of the most difficult to treat malignancies in pediatrics. Hence, new knowledge of potential targets for therapeutics and the development of novel treatment approach...

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Bibliographic Details
Main Authors: Jayanthan Aarthi, Bernoux Delphine, Bose Pinaki, Riabowol Karl, Narendran Aru
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/11/1/44

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