Exosomal PD-L1 and N-cadherin predict pulmonary metastasis progression for osteosarcoma patients

Exosomal PD-L1 and N-cadherin predict pulmonary metastasis progression for osteosarcoma patients

Abstract Background Recent studies indicated that exosomal programmed death-ligand 1 (PD-L1) derived from cancers could induce immunosuppression and tumor pathogenesis. However, it is unclear how exosomes influence osteosarcoma (OS) progression and whether PD-L1 also exists in serum exosomes (Sr-exo...

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Bibliographic Details
Main Authors: Jun Wang, Hongliang Zhang, Xin Sun, Xiaofang Wang, Tingting Ren, Yi Huang, Ranxin Zhang, Bingxin Zheng, Wei Guo
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Nanobiotechnology
Subjects:
Exosome
programmed death-ligand 1
N-cadherin
osteosarcoma
biomarker
Online Access:http://link.springer.com/article/10.1186/s12951-020-00710-6

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