Metabolic PET/CT analysis of aggressive Non-Hodgkin lymphoma prior to Axicabtagene Ciloleucel CAR-T infusion: predictors of progressive disease, survival, and toxicity

Metabolic PET/CT analysis of aggressive Non-Hodgkin lymphoma prior to Axicabtagene Ciloleucel CAR-T infusion: predictors of progressive disease, survival, and toxicity

Abstract PET/CT is used to evaluate relapsed/refractory non-Hodgkin lymphoma (NHL) prior to chimeric antigen receptor T-cell (CAR-T) infusion at two time points: pre-leukapheresis (pre-leuk) and pre-lymphodepletion chemotherapy (pre-LD). We hypothesized that changes in PET/CT between these time poin...

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Bibliographic Details
Main Authors: William G. Breen, Jason R. Young, Matthew A. Hathcock, Roman O. Kowalchuk, Matthew P. Thorpe, Radhika Bansal, Arushi Khurana, N. Nora Bennani, Jonas Paludo, Jose Villasboas Bisneto, Yucai Wang, Stephen M. Ansell, Jennifer L. Peterson, Patrick B. Johnston, Scott C. Lester, Yi Lin
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-023-00895-7

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