New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis

Purpose: Cardiac metastasis is a rare fatal event. An intracavitary right tumor mainly in the ventricle is difficult to manage. Literature reports suggest that cardiac surgery in oligometastatic patients could offer median survival of 1 year. We investigated salvage treatment comprising transcoronar...

Full description

Bibliographic Details
Main Authors: Sylvie Delanian, Sameh Awad, Aimery de Gramont
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Clinical and Translational Radiation Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630821000896
Description
Summary:Purpose: Cardiac metastasis is a rare fatal event. An intracavitary right tumor mainly in the ventricle is difficult to manage. Literature reports suggest that cardiac surgery in oligometastatic patients could offer median survival of 1 year. We investigated salvage treatment comprising transcoronary tumor embolization followed 15 days later by cardiac radiotherapy (40.5 Gy/15 fractions). Cases: We report two cases of severe right cardiac metastasis with a history of abdominal cancer managed by this salvage treatment following residual cardiac mass after previous cardiac surgery. Conclusion: Both symptomatic patients improved progressively and were locally controlled for at least 1 year without toxicity.
ISSN:2405-6308