New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis

Purpose: Cardiac metastasis is a rare fatal event. An intracavitary right tumor mainly in the ventricle is difficult to manage. Literature reports suggest that cardiac surgery in oligometastatic patients could offer median survival of 1 year. We investigated salvage treatment comprising transcoronar...

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Main Authors: Sylvie Delanian, Sameh Awad, Aimery de Gramont
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Clinical and Translational Radiation Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630821000896
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author Sylvie Delanian
Sameh Awad
Aimery de Gramont
author_facet Sylvie Delanian
Sameh Awad
Aimery de Gramont
author_sort Sylvie Delanian
collection DOAJ
description Purpose: Cardiac metastasis is a rare fatal event. An intracavitary right tumor mainly in the ventricle is difficult to manage. Literature reports suggest that cardiac surgery in oligometastatic patients could offer median survival of 1 year. We investigated salvage treatment comprising transcoronary tumor embolization followed 15 days later by cardiac radiotherapy (40.5 Gy/15 fractions). Cases: We report two cases of severe right cardiac metastasis with a history of abdominal cancer managed by this salvage treatment following residual cardiac mass after previous cardiac surgery. Conclusion: Both symptomatic patients improved progressively and were locally controlled for at least 1 year without toxicity.
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spelling doaj.art-2218a03a9a8f4d65a601cf10f1babf8a2022-12-22T04:09:02ZengElsevierClinical and Translational Radiation Oncology2405-63082022-01-013215New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasisSylvie Delanian0Sameh Awad1Aimery de Gramont2Oncologie-Radiothérapie, Groupe Hospitalier Universitaire, APHP site Saint-Louis-Université de Paris, France; Centre de Cancérologie de la Porte de Saint Cloud-Hôpital Américain de Paris, Boulogne, France; Corresponding author at: Oncologie-Radiothérapie, Radiopathologie, Hôpital Saint Louis, APHP, 1, Ave Claude Vellefaux, 75010 Paris, France.Radiologie Interventionnelle, Clinique Ambroise Paré, Neuilly-Sur-Seine, FranceOncologie Médicale, Hôpital Franco-Britanique, Levallois-Perret, FrancePurpose: Cardiac metastasis is a rare fatal event. An intracavitary right tumor mainly in the ventricle is difficult to manage. Literature reports suggest that cardiac surgery in oligometastatic patients could offer median survival of 1 year. We investigated salvage treatment comprising transcoronary tumor embolization followed 15 days later by cardiac radiotherapy (40.5 Gy/15 fractions). Cases: We report two cases of severe right cardiac metastasis with a history of abdominal cancer managed by this salvage treatment following residual cardiac mass after previous cardiac surgery. Conclusion: Both symptomatic patients improved progressively and were locally controlled for at least 1 year without toxicity.http://www.sciencedirect.com/science/article/pii/S2405630821000896Cardiac metastasisRadiotherapyTranscatheter arterial embolizationCardiac imaging
spellingShingle Sylvie Delanian
Sameh Awad
Aimery de Gramont
New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
Clinical and Translational Radiation Oncology
Cardiac metastasis
Radiotherapy
Transcatheter arterial embolization
Cardiac imaging
title New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
title_full New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
title_fullStr New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
title_full_unstemmed New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
title_short New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
title_sort new curative approach using embolization followed by moderate dose radiotherapy after surgical failure for large right heart metastasis
topic Cardiac metastasis
Radiotherapy
Transcatheter arterial embolization
Cardiac imaging
url http://www.sciencedirect.com/science/article/pii/S2405630821000896
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