Application of Sensing Techniques to Cellular Force Measurement
Cell traction forces (CTFs) are the forces produced by cells and exerted on extracellular matrix or an underlying substrate. CTFs function to maintain cell shape, enable cell migration, and generate and detect mechanical signals. As such, they play a vital role in many fundamental biological process...
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| Format: | Article |
| Language: | English |
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MDPI AG
2010-11-01
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| Series: | Sensors |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1424-8220/10/11/9948/ |
| _version_ | 1828349467375435776 |
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| author | James H.-C. Wang Bin Li |
| author_facet | James H.-C. Wang Bin Li |
| author_sort | James H.-C. Wang |
| collection | DOAJ |
| description | Cell traction forces (CTFs) are the forces produced by cells and exerted on extracellular matrix or an underlying substrate. CTFs function to maintain cell shape, enable cell migration, and generate and detect mechanical signals. As such, they play a vital role in many fundamental biological processes, including angiogenesis, inflammation, and wound healing. Therefore, a close examination of CTFs can enable better understanding of the cellular and molecular mechanisms of such processes. To this end, various force-sensing techniques for CTF measurement have been developed over the years. This article will provide a concise review of these sensing techniques and comment on the needs for improved force-sensing technologies for cell mechanics and biology research. |
| first_indexed | 2024-04-14T01:10:56Z |
| format | Article |
| id | doaj.art-2219a772b7114f19851405ccab3bb5a4 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-14T01:10:56Z |
| publishDate | 2010-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-2219a772b7114f19851405ccab3bb5a42022-12-22T02:21:04ZengMDPI AGSensors1424-82202010-11-0110119948996210.3390/s101109948Application of Sensing Techniques to Cellular Force MeasurementJames H.-C. WangBin LiCell traction forces (CTFs) are the forces produced by cells and exerted on extracellular matrix or an underlying substrate. CTFs function to maintain cell shape, enable cell migration, and generate and detect mechanical signals. As such, they play a vital role in many fundamental biological processes, including angiogenesis, inflammation, and wound healing. Therefore, a close examination of CTFs can enable better understanding of the cellular and molecular mechanisms of such processes. To this end, various force-sensing techniques for CTF measurement have been developed over the years. This article will provide a concise review of these sensing techniques and comment on the needs for improved force-sensing technologies for cell mechanics and biology research.http://www.mdpi.com/1424-8220/10/11/9948/cell traction forcemeasurementcell force monitormicropost force sensor arraycell traction force microscopy |
| spellingShingle | James H.-C. Wang Bin Li Application of Sensing Techniques to Cellular Force Measurement Sensors cell traction force measurement cell force monitor micropost force sensor array cell traction force microscopy |
| title | Application of Sensing Techniques to Cellular Force Measurement |
| title_full | Application of Sensing Techniques to Cellular Force Measurement |
| title_fullStr | Application of Sensing Techniques to Cellular Force Measurement |
| title_full_unstemmed | Application of Sensing Techniques to Cellular Force Measurement |
| title_short | Application of Sensing Techniques to Cellular Force Measurement |
| title_sort | application of sensing techniques to cellular force measurement |
| topic | cell traction force measurement cell force monitor micropost force sensor array cell traction force microscopy |
| url | http://www.mdpi.com/1424-8220/10/11/9948/ |
| work_keys_str_mv | AT jameshcwang applicationofsensingtechniquestocellularforcemeasurement AT binli applicationofsensingtechniquestocellularforcemeasurement |