Cerebral infarction associated with benign mucin-producing adenomyosis: report of two cases
Abstract Background Cerebral infarction associated with a malignant tumor is widely recognized as Trousseau syndrome. In contrast, few cases of cerebral infarction associated with benign tumors have been reported. We present two cases of embolic stroke that seemed to be caused by mucin-producing ade...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-10-01
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| Series: | BMC Neurology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12883-018-1169-2 |
| _version_ | 1818196853055815680 |
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| author | Koki Okazaki Fumiaki Oka Hideyuki Ishihara Michiyasu Suzuki |
| author_facet | Koki Okazaki Fumiaki Oka Hideyuki Ishihara Michiyasu Suzuki |
| author_sort | Koki Okazaki |
| collection | DOAJ |
| description | Abstract Background Cerebral infarction associated with a malignant tumor is widely recognized as Trousseau syndrome. In contrast, few cases of cerebral infarction associated with benign tumors have been reported. We present two cases of embolic stroke that seemed to be caused by mucin-producing adenomyosis. Case presentation The patients were women aged 42 and 50 years old. Both patients developed right hemiparesis and aphasia, and cerebral infarctions were detected in the left cerebral hemisphere. There were no other abnormal findings, except for elevation of CA125 and D-dimer. Trousseau syndrome was suspected in both cases, but whole body examinations did not reveal any malignant tumors. However, uterine adenomyosis was detected in both patients. Conclusions From our findings and a review of the literature, both mucin-producing malignant tumors and mucin-producing benign tumors such as adenomyosis may cause hypercoagulability and cerebral infarction. This mechanism should be considered in a case of a young to middle-aged woman with embolic stroke of an undetermined origin. |
| first_indexed | 2024-12-12T01:40:40Z |
| format | Article |
| id | doaj.art-221ae0abbdad4f4bb5e5df5ad314dab6 |
| institution | Directory Open Access Journal |
| issn | 1471-2377 |
| language | English |
| last_indexed | 2024-12-12T01:40:40Z |
| publishDate | 2018-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj.art-221ae0abbdad4f4bb5e5df5ad314dab62022-12-22T00:42:42ZengBMCBMC Neurology1471-23772018-10-011811410.1186/s12883-018-1169-2Cerebral infarction associated with benign mucin-producing adenomyosis: report of two casesKoki Okazaki0Fumiaki Oka1Hideyuki Ishihara2Michiyasu Suzuki3Department of Neurosurgery, Yamaguchi University School of MedicineDepartment of Neurosurgery, Yamaguchi University School of MedicineDepartment of Neurosurgery, Yamaguchi University School of MedicineDepartment of Neurosurgery, Yamaguchi University School of MedicineAbstract Background Cerebral infarction associated with a malignant tumor is widely recognized as Trousseau syndrome. In contrast, few cases of cerebral infarction associated with benign tumors have been reported. We present two cases of embolic stroke that seemed to be caused by mucin-producing adenomyosis. Case presentation The patients were women aged 42 and 50 years old. Both patients developed right hemiparesis and aphasia, and cerebral infarctions were detected in the left cerebral hemisphere. There were no other abnormal findings, except for elevation of CA125 and D-dimer. Trousseau syndrome was suspected in both cases, but whole body examinations did not reveal any malignant tumors. However, uterine adenomyosis was detected in both patients. Conclusions From our findings and a review of the literature, both mucin-producing malignant tumors and mucin-producing benign tumors such as adenomyosis may cause hypercoagulability and cerebral infarction. This mechanism should be considered in a case of a young to middle-aged woman with embolic stroke of an undetermined origin.http://link.springer.com/article/10.1186/s12883-018-1169-2Cerebral infarctionAdenomyosisTrousseau’s syndromeBenign tumorCase report |
| spellingShingle | Koki Okazaki Fumiaki Oka Hideyuki Ishihara Michiyasu Suzuki Cerebral infarction associated with benign mucin-producing adenomyosis: report of two cases BMC Neurology Cerebral infarction Adenomyosis Trousseau’s syndrome Benign tumor Case report |
| title | Cerebral infarction associated with benign mucin-producing adenomyosis: report of two cases |
| title_full | Cerebral infarction associated with benign mucin-producing adenomyosis: report of two cases |
| title_fullStr | Cerebral infarction associated with benign mucin-producing adenomyosis: report of two cases |
| title_full_unstemmed | Cerebral infarction associated with benign mucin-producing adenomyosis: report of two cases |
| title_short | Cerebral infarction associated with benign mucin-producing adenomyosis: report of two cases |
| title_sort | cerebral infarction associated with benign mucin producing adenomyosis report of two cases |
| topic | Cerebral infarction Adenomyosis Trousseau’s syndrome Benign tumor Case report |
| url | http://link.springer.com/article/10.1186/s12883-018-1169-2 |
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