Patient with MADSAM, Autoimmune Thyroiditis and 6th Cranial Nerve Paralysis
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a sensory and motor demyelinating polyneuropathy that occurs with autoimmune mechanisms, affects the spinal roots, plexuses, and peripheral nerves, and presents with attacks or progressivity. Proximal and/or distal strength loss and...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2021-09-01
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| Series: | Türk Nöroloji Dergisi |
| Subjects: | |
| Online Access: | https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-24922&look4= |
| _version_ | 1828015617141112832 |
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| author | Buket Özkara Faik Budak |
| author_facet | Buket Özkara Faik Budak |
| author_sort | Buket Özkara |
| collection | DOAJ |
| description | Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a sensory and motor demyelinating polyneuropathy that occurs with autoimmune mechanisms, affects the spinal roots, plexuses, and peripheral nerves, and presents with attacks or progressivity. Proximal and/or distal strength loss and mild atrophy in the upper and lower extremities and sensory complaints, such as numbness, pain, and burning, are observed. Cranial nerve involvement rarely accompanies typical findings. Facial nerve involvement is the most common; however, trigeminal, oculomotor, hypoglossus, and abducens nerve involvements are reported. Multifocal acquired demyelinating sensory and motor neuropathy (MADSAM) is an atypical variant of CIDP, characterized by asymmetrical motor and sensory losses and conduction blocks in the electromyography. Hashimoto’s thyroiditis is an autoimmune disease diagnosed with high serum thyroid antibody concentrations. Coexistence with neurological autoimmune diseases such as multiple sclerosis, myasthenia gravis, and multifocal motor neuropathy was reported. Moreover, few studies showed the coexistence of Hashimato’s thyroiditis and CIDP in the literature. Presented herein is a case of MADSAM with cranial nerve involvement and Hashimato’s thyroiditis. |
| first_indexed | 2024-04-10T10:20:49Z |
| format | Article |
| id | doaj.art-221d883f584545259890443b76e244fd |
| institution | Directory Open Access Journal |
| issn | 1309-2545 |
| language | English |
| last_indexed | 2024-04-10T10:20:49Z |
| publishDate | 2021-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Nöroloji Dergisi |
| spelling | doaj.art-221d883f584545259890443b76e244fd2023-02-15T16:21:38ZengGalenos YayineviTürk Nöroloji Dergisi1309-25452021-09-0127331131410.4274/tnd.2021.24922Patient with MADSAM, Autoimmune Thyroiditis and 6th Cranial Nerve ParalysisBuket Özkara0https://orcid.org/0000-0002-1033-7737Faik Budak1https://orcid.org/0000-0002-3068-1423Alanya Alaaddin Keykubat University Faculty of Medicine, Department of Neurology, Antalya, TurkeyKocaeli University Faculty of Medicine, Department of Neurology, Kocaeli, TurkeyChronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a sensory and motor demyelinating polyneuropathy that occurs with autoimmune mechanisms, affects the spinal roots, plexuses, and peripheral nerves, and presents with attacks or progressivity. Proximal and/or distal strength loss and mild atrophy in the upper and lower extremities and sensory complaints, such as numbness, pain, and burning, are observed. Cranial nerve involvement rarely accompanies typical findings. Facial nerve involvement is the most common; however, trigeminal, oculomotor, hypoglossus, and abducens nerve involvements are reported. Multifocal acquired demyelinating sensory and motor neuropathy (MADSAM) is an atypical variant of CIDP, characterized by asymmetrical motor and sensory losses and conduction blocks in the electromyography. Hashimoto’s thyroiditis is an autoimmune disease diagnosed with high serum thyroid antibody concentrations. Coexistence with neurological autoimmune diseases such as multiple sclerosis, myasthenia gravis, and multifocal motor neuropathy was reported. Moreover, few studies showed the coexistence of Hashimato’s thyroiditis and CIDP in the literature. Presented herein is a case of MADSAM with cranial nerve involvement and Hashimato’s thyroiditis.https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-24922&look4=madsamautoimmune thyroiditiscranial nerve paralysis |
| spellingShingle | Buket Özkara Faik Budak Patient with MADSAM, Autoimmune Thyroiditis and 6th Cranial Nerve Paralysis Türk Nöroloji Dergisi madsam autoimmune thyroiditis cranial nerve paralysis |
| title | Patient with MADSAM, Autoimmune Thyroiditis and 6th Cranial Nerve Paralysis |
| title_full | Patient with MADSAM, Autoimmune Thyroiditis and 6th Cranial Nerve Paralysis |
| title_fullStr | Patient with MADSAM, Autoimmune Thyroiditis and 6th Cranial Nerve Paralysis |
| title_full_unstemmed | Patient with MADSAM, Autoimmune Thyroiditis and 6th Cranial Nerve Paralysis |
| title_short | Patient with MADSAM, Autoimmune Thyroiditis and 6th Cranial Nerve Paralysis |
| title_sort | patient with madsam autoimmune thyroiditis and 6th cranial nerve paralysis |
| topic | madsam autoimmune thyroiditis cranial nerve paralysis |
| url | https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-24922&look4= |
| work_keys_str_mv | AT buketozkara patientwithmadsamautoimmunethyroiditisand6thcranialnerveparalysis AT faikbudak patientwithmadsamautoimmunethyroiditisand6thcranialnerveparalysis |