Low GILT expression is associated with poor patient survival in diffuse large B-cell lymphoma

Low GILT expression is associated with poor patient survival in diffuse large B-cell lymphoma

The MHC class II-restricted antigen processing pathway presents antigenic peptides acquired in the endocytic route for the activation of CD4+ T cells. Multiple cancers express MHC class II, which may influence the anti-tumor immune response and patient outcome. Low MHC class II expression is assoc...

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Bibliographic Details
Main Authors: Hannah ePhipps-Yonas, Haiyan eCui, Noemi eSebastiao, Patrick S. Brunhoeber, Ellen eHaddock, Martin J. Deymier, Wolfram eKlapper, Lonnie eLybarger, Denise eRoe, Karen Taraszka Hastings
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
antigen processing and presentation
tumor immunology
GILT
MHC class II
diffuse large B cell lymphoma
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00425/full

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