MiR-520a-3p Inhibited Macrophage Polarization and Promoted the Development of Atherosclerosis via Targeting UVRAG in Apolipoprotein E Knockout Mice

MiR-520a-3p Inhibited Macrophage Polarization and Promoted the Development of Atherosclerosis via Targeting UVRAG in Apolipoprotein E Knockout Mice

Atherosclerosis (AS), a kind of chronic inflammatory blood vessel disease, is a main cause of cardiovascular disease, which is a leading cause of mortality around the world. Accumulation of macrophages induced by inflammation contributes to AS development. It has been indicated that microRNAs (miRNA...

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Bibliographic Details
Main Authors: Jing Rui Qi, Dian Ru Zhao, Li Zhao, Fan Luo, Mei Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
MiR-520a-3p
macrophage polarization
autophagy
atherosclerosis
chronic inflammatory blood vessel disease
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.621324/full

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