Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease

Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease

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The SARS-CoV-2 coronavirus has led to a pandemic with millions of people affected. The present study finds that risk-factors for severe COVID-19 disease courses, i.e. male sex, older age and sedentary life style are associated with higher prostaglandin E2 (PGE2) serum levels in blood samples from un...

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Bibliographic Details
Main Authors: Melanie Ricke-Hoch, Elisabeth Stelling, Lisa Lasswitz, Antonia P. Gunesch, Martina Kasten, Francisco J. Zapatero-Belinchón, Graham Brogden, Gisa Gerold, Thomas Pietschmann, Virginie Montiel, Jean-Luc Balligand, Federica Facciotti, Emilio Hirsch, Thomas Gausepohl, Husni Elbahesh, Guus F. Rimmelzwaan, Anne Höfer, Mark P. Kühnel, Danny Jonigk, Julian Eigendorf, Uwe Tegtbur, Lena Mink, Michaela Scherr, Thomas Illig, Axel Schambach, Tobias J. Pfeffer, Andres Hilfiker, Axel Haverich, Denise Hilfiker-Kleiner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336874/?tool=EBI

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