Celiac disease - a review on recent advances in characteristics, diagnostic and treatments
Introduction and purpose: Celiac disease occurs in 1% of the general population. However, many cases remain unrecognized. The disease is a chronic immune-mediated disorder triggered by the ingestion of gluten that appears in individuals with genetic susceptibility. Celiac disease can develop...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2022-11-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/40835 |
| _version_ | 1797986972012118016 |
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| author | Klaudia Artykiewicz Marcin Czarkowski Kamila Gorczyca Maria Grodkiewicz Paweł Kozieł Urszula Krzysiek Klaudia Podgórska Aleksandra Puła Aleksandra Słupczyńska Weronika Urbaś |
| author_facet | Klaudia Artykiewicz Marcin Czarkowski Kamila Gorczyca Maria Grodkiewicz Paweł Kozieł Urszula Krzysiek Klaudia Podgórska Aleksandra Puła Aleksandra Słupczyńska Weronika Urbaś |
| author_sort | Klaudia Artykiewicz |
| collection | DOAJ |
| description |
Introduction and purpose:
Celiac disease occurs in 1% of the general population. However, many cases remain unrecognized.
The disease is a chronic immune-mediated disorder triggered by the ingestion of gluten that appears in individuals with genetic susceptibility. Celiac disease can develop in paediatric patients as well as adults.
The purpose of this review is to analyze the newest information on the characteristics, diagnosis and treatment of patients with celiac disease.
Material and methods:
This review was based on available data collected in the PubMed database and published between 2015 and 2022. The research was done by looking through keywords such as: “celiac disease”, “Gluten-Free Diet”, “diagnosis” and “treatment”.
Results:
The diagnosis of celiac disease is most often delayed due to the broad spectrum of presentations. Screening of at-risk individuals is important to progress the diagnosis.
It is additionally crucial to raise clinicians' attention to non-specific parenteral symptoms that may indicate celiac disease. The majority of the symptoms arise from nutritional deficiencies caused by intestinal malabsorption. According to scientific reports, the most common deficiencies of people with celiac disease are iron, folic acid, vitamin B12, fat-soluble vitamins and a calcium.
Conclusions:
Recent years have seen the emergence of research into new therapeutic options, but their efficacy and safety still need to be evaluated more thoroughly. Strict adherence to a gluten-free diet by patients is still the only treatment option at present.
Celiac disease, due to the constant increase in knowledge about its pathogenesis, diagnosis and treatment is an important material for further research.
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| first_indexed | 2024-04-11T07:40:27Z |
| format | Article |
| id | doaj.art-2230f20c81ae4450a174c8d30cceab0b |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-04-11T07:40:27Z |
| publishDate | 2022-11-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-2230f20c81ae4450a174c8d30cceab0b2022-12-22T04:36:33ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062022-11-0113110.12775/JEHS.2023.13.01.001Celiac disease - a review on recent advances in characteristics, diagnostic and treatmentsKlaudia Artykiewicz0Marcin Czarkowski1Kamila Gorczyca2Maria Grodkiewicz3Paweł Kozieł4Urszula Krzysiek5Klaudia PodgórskaAleksandra Puła6Aleksandra Słupczyńska7Weronika Urbaś8Samodzielny Publiczny Szpital Kliniczny nr 4 w Lublinie, ul. Doktora Kazimierza Jaczewskiego 8, 20-954 LublinUniwersytet Medyczny w LublinieSamodzielny Publiczny Szpital Kliniczny Nr 4 w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieSzpital Solec Spółka z Ograniczoną Odpowiedzialnością w WarszawieWojewódzki Szpital Specjalistyczny im. Kardynała Stefana Wyszyńskiego SPOZ w LublinieSamodzielny Publiczny Szpital Kliniczny Nr 1 w LublinieUniwersytet Medyczny w Lublinie Introduction and purpose: Celiac disease occurs in 1% of the general population. However, many cases remain unrecognized. The disease is a chronic immune-mediated disorder triggered by the ingestion of gluten that appears in individuals with genetic susceptibility. Celiac disease can develop in paediatric patients as well as adults. The purpose of this review is to analyze the newest information on the characteristics, diagnosis and treatment of patients with celiac disease. Material and methods: This review was based on available data collected in the PubMed database and published between 2015 and 2022. The research was done by looking through keywords such as: “celiac disease”, “Gluten-Free Diet”, “diagnosis” and “treatment”. Results: The diagnosis of celiac disease is most often delayed due to the broad spectrum of presentations. Screening of at-risk individuals is important to progress the diagnosis. It is additionally crucial to raise clinicians' attention to non-specific parenteral symptoms that may indicate celiac disease. The majority of the symptoms arise from nutritional deficiencies caused by intestinal malabsorption. According to scientific reports, the most common deficiencies of people with celiac disease are iron, folic acid, vitamin B12, fat-soluble vitamins and a calcium. Conclusions: Recent years have seen the emergence of research into new therapeutic options, but their efficacy and safety still need to be evaluated more thoroughly. Strict adherence to a gluten-free diet by patients is still the only treatment option at present. Celiac disease, due to the constant increase in knowledge about its pathogenesis, diagnosis and treatment is an important material for further research. https://apcz.umk.pl/JEHS/article/view/40835celiac diseasegluten-free dietdiagnosistreatment |
| spellingShingle | Klaudia Artykiewicz Marcin Czarkowski Kamila Gorczyca Maria Grodkiewicz Paweł Kozieł Urszula Krzysiek Klaudia Podgórska Aleksandra Puła Aleksandra Słupczyńska Weronika Urbaś Celiac disease - a review on recent advances in characteristics, diagnostic and treatments Journal of Education, Health and Sport celiac disease gluten-free diet diagnosis treatment |
| title | Celiac disease - a review on recent advances in characteristics, diagnostic and treatments |
| title_full | Celiac disease - a review on recent advances in characteristics, diagnostic and treatments |
| title_fullStr | Celiac disease - a review on recent advances in characteristics, diagnostic and treatments |
| title_full_unstemmed | Celiac disease - a review on recent advances in characteristics, diagnostic and treatments |
| title_short | Celiac disease - a review on recent advances in characteristics, diagnostic and treatments |
| title_sort | celiac disease a review on recent advances in characteristics diagnostic and treatments |
| topic | celiac disease gluten-free diet diagnosis treatment |
| url | https://apcz.umk.pl/JEHS/article/view/40835 |
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