Dihydrotanshinone I Inhibits the Proliferation and Growth of Oxaliplatin-Resistant Human HCT116 Colorectal Cancer Cells

Dihydrotanshinone I Inhibits the Proliferation and Growth of Oxaliplatin-Resistant Human HCT116 Colorectal Cancer Cells

Oxaliplatin (OXA) is a first-line chemotherapeutic drug for the treatment of colorectal cancer (CRC), but acquired drug resistance becomes the main cause of treatment failure. Increasing evidence has shown that some natural components may serve as chemoresistant sensitizers. In this study, we discov...

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Bibliographic Details
Main Authors: Mengge Wang, Yusen Xiang, Ruyu Wang, Lijun Zhang, Hong Zhang, Hongzhuan Chen, Xin Luan, Lili Chen
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
Dihydrotanshinone I
CRC
oxaliplatin-resistant
virtual screening
SHP2
Online Access:https://www.mdpi.com/1420-3049/27/22/7774

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