Evaluation of chromatin mesoscale organization
Chromatin organization in the nucleus represents an important aspect of transcription regulation. Most of the studies so far focused on the chromatin structure in cultured cells or in fixed tissue preparations. Here, we discuss the various approaches for deciphering chromatin 3D organization with an...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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AIP Publishing LLC
2022-03-01
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| Series: | APL Bioengineering |
| Online Access: | http://dx.doi.org/10.1063/5.0069286 |
| _version_ | 1819047404091998208 |
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| author | Dana Lorber Talila Volk |
| author_facet | Dana Lorber Talila Volk |
| author_sort | Dana Lorber |
| collection | DOAJ |
| description | Chromatin organization in the nucleus represents an important aspect of transcription regulation. Most of the studies so far focused on the chromatin structure in cultured cells or in fixed tissue preparations. Here, we discuss the various approaches for deciphering chromatin 3D organization with an emphasis on the advantages of live imaging approaches. |
| first_indexed | 2024-12-21T10:59:49Z |
| format | Article |
| id | doaj.art-223351215f6240f68581684829449f49 |
| institution | Directory Open Access Journal |
| issn | 2473-2877 |
| language | English |
| last_indexed | 2024-12-21T10:59:49Z |
| publishDate | 2022-03-01 |
| publisher | AIP Publishing LLC |
| record_format | Article |
| series | APL Bioengineering |
| spelling | doaj.art-223351215f6240f68581684829449f492022-12-21T19:06:22ZengAIP Publishing LLCAPL Bioengineering2473-28772022-03-0161010902010902-610.1063/5.0069286Evaluation of chromatin mesoscale organizationDana Lorber0Talila Volk1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, IsraelDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, IsraelChromatin organization in the nucleus represents an important aspect of transcription regulation. Most of the studies so far focused on the chromatin structure in cultured cells or in fixed tissue preparations. Here, we discuss the various approaches for deciphering chromatin 3D organization with an emphasis on the advantages of live imaging approaches.http://dx.doi.org/10.1063/5.0069286 |
| spellingShingle | Dana Lorber Talila Volk Evaluation of chromatin mesoscale organization APL Bioengineering |
| title | Evaluation of chromatin mesoscale organization |
| title_full | Evaluation of chromatin mesoscale organization |
| title_fullStr | Evaluation of chromatin mesoscale organization |
| title_full_unstemmed | Evaluation of chromatin mesoscale organization |
| title_short | Evaluation of chromatin mesoscale organization |
| title_sort | evaluation of chromatin mesoscale organization |
| url | http://dx.doi.org/10.1063/5.0069286 |
| work_keys_str_mv | AT danalorber evaluationofchromatinmesoscaleorganization AT talilavolk evaluationofchromatinmesoscaleorganization |