Co-Expression of Androgen Receptor and Cathepsin D Defines a Triple-Negative Breast Cancer Subgroup with Poorer Overall Survival

Co-Expression of Androgen Receptor and Cathepsin D Defines a Triple-Negative Breast Cancer Subgroup with Poorer Overall Survival

Background: In the triple-negative breast cancer (TNBC) group, the luminal androgen receptor subtype is characterized by expression of androgen receptor (AR) and lack of estrogen receptor and cytokeratin 5/6 expression. Cathepsin D (Cath-D) is overproduced and hypersecreted by breast cancer (BC) cel...

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Bibliographic Details
Main Authors: Hanane Mansouri, Lindsay B. Alcaraz, Caroline Mollevi, Aude Mallavialle, William Jacot, Florence Boissière-Michot, Joelle Simony-Lafontaine, Valérie Laurent-Matha, Pascal Roger, Emmanuelle Liaudet-Coopman, Séverine Guiu
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
androgen receptor
cathepsin D
triple-negative breast cancer
prognosis
Online Access:https://www.mdpi.com/2072-6694/12/5/1244

Internet

https://www.mdpi.com/2072-6694/12/5/1244

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