Design and Production of a Recombinant Hybrid Toxin to Raise Protective Antibodies against <em>Loxosceles</em> Spider Venom

Design and Production of a Recombinant Hybrid Toxin to Raise Protective Antibodies against <em>Loxosceles</em> Spider Venom

Human accidents with spiders of the genus <i>Loxosceles</i> are an important health problem affecting thousands of people worldwide. Patients evolve to severe local injuries and, in many cases, to systemic disturbances as acute renal failure, in which cases antivenoms are considered to b...

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Bibliographic Details
Main Authors: Paula A. L. Calabria, Lhiri Hanna A. L. Shimokawa-Falcão, Monica Colombini, Ana M. Moura-da-Silva, Katia C. Barbaro, Eliana L. Faquim-Mauro, Geraldo S. Magalhaes
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Toxins
Subjects:
phospholipases D
metalloproteases
<i>Loxosceles</i> spp.
recombinant toxins
hybrid immunogen
neutralizing antibodies
antivenoms
Online Access:https://www.mdpi.com/2072-6651/11/2/108

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