Severity of SARS-CoV-2 Omicron XBB subvariants in Singapore

Severity of SARS-CoV-2 Omicron XBB subvariants in Singapore

Summary: Several XBB subvariants such as XBB.1.5, XBB.1.9, XBB.1.16 and XBB.2.3 co-circulate in Singapore. Despite the different viral properties of XBB.1.16 as compared to other XBB subvariants, comparison on their severity is limited. In this study, we investigate the outcomes of hospitalisation a...

Full description

Bibliographic Details
Main Authors: Rachael Pung, Xin Peng Kong, Lin Cui, Sae-Rom Chae, Mark I-Cheng Chen, Vernon J. Lee, Zheng Jie Marc Ho
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:The Lancet Regional Health. Western Pacific
Online Access:http://www.sciencedirect.com/science/article/pii/S2666606523001670
Description
Summary:Summary: Several XBB subvariants such as XBB.1.5, XBB.1.9, XBB.1.16 and XBB.2.3 co-circulate in Singapore. Despite the different viral properties of XBB.1.16 as compared to other XBB subvariants, comparison on their severity is limited. In this study, we investigate the outcomes of hospitalisation and severe COVID-19 infection in individuals infected with different XBB subvariants, adjusted for potential confounders such as age and vaccination history. Overall, our preliminary analysis showed that the risk of severe outcomes when infected with XBB.1.16 is higher than that of XBB.1.5 or XBB.1.9 but there is no difference in the risk of hospitalisation across different XBB subvariants.
ISSN:2666-6065

Similar Items