Study of Surrogate Immunohistochemical Markers IDH1, ATRX, BRAF V600E, and p53 Mutation in Astrocytic and Oligodendroglial Tumors
Introduction In consonance with current the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (2016), histological diagnosis of gliomas should be reinforced by molecular information. This study was performed to determine the frequency of isocitrate...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical Publishers, Inc.
2023-08-01
|
| Series: | Indian Journal of Neurosurgery |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1743265 |
| _version_ | 1827866683685994496 |
|---|---|
| author | Santosh Sharma Kusum Mathur Alka Mittal Meel Mukta Arpita Jindal Mukesh Kumar |
| author_facet | Santosh Sharma Kusum Mathur Alka Mittal Meel Mukta Arpita Jindal Mukesh Kumar |
| author_sort | Santosh Sharma |
| collection | DOAJ |
| description |
Introduction In consonance with current the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (2016), histological diagnosis of gliomas should be reinforced by molecular information. This study was performed to determine the frequency of isocitrate dehydrogenase 1 (IDH1), α thalassemia/intellectual disability syndrome X-linked (ATRX), p53, and BRAF V600E mutations in different grade astrocytomas and oligodendrogliomas. |
| first_indexed | 2024-03-12T15:08:57Z |
| format | Article |
| id | doaj.art-22399656e39f4a829ca799e82d7e8621 |
| institution | Directory Open Access Journal |
| issn | 2277-954X 2277-9167 |
| language | English |
| last_indexed | 2024-03-12T15:08:57Z |
| publishDate | 2023-08-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Indian Journal of Neurosurgery |
| spelling | doaj.art-22399656e39f4a829ca799e82d7e86212023-08-11T23:49:34ZengThieme Medical Publishers, Inc.Indian Journal of Neurosurgery2277-954X2277-91672023-08-01120213714610.1055/s-0042-1743265Study of Surrogate Immunohistochemical Markers IDH1, ATRX, BRAF V600E, and p53 Mutation in Astrocytic and Oligodendroglial TumorsSantosh Sharma0Kusum Mathur1Alka Mittal2Meel Mukta3https://orcid.org/0000-0001-7788-8608Arpita Jindal4Mukesh Kumar5SMS Medical College and Attached Hospital, Jaipur, Rajasthan, IndiaSMS Medical College and Attached Hospital, Jaipur, Rajasthan, IndiaSMS Medical College and Attached Hospital, Jaipur, Rajasthan, IndiaSMS Medical College and Attached Hospital, Jaipur, Rajasthan, IndiaSMS Medical College and Attached Hospital, Jaipur, Rajasthan, IndiaSMS Medical College and Attached Hospital, Jaipur, Rajasthan, India Introduction In consonance with current the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (2016), histological diagnosis of gliomas should be reinforced by molecular information. This study was performed to determine the frequency of isocitrate dehydrogenase 1 (IDH1), α thalassemia/intellectual disability syndrome X-linked (ATRX), p53, and BRAF V600E mutations in different grade astrocytomas and oligodendrogliomas.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1743265astrocytomaoligodendrogliomaglioblastomaisocitratedehydrogenase |
| spellingShingle | Santosh Sharma Kusum Mathur Alka Mittal Meel Mukta Arpita Jindal Mukesh Kumar Study of Surrogate Immunohistochemical Markers IDH1, ATRX, BRAF V600E, and p53 Mutation in Astrocytic and Oligodendroglial Tumors Indian Journal of Neurosurgery astrocytoma oligodendroglioma glioblastoma isocitrate dehydrogenase |
| title | Study of Surrogate Immunohistochemical Markers IDH1, ATRX, BRAF V600E, and p53 Mutation in Astrocytic and Oligodendroglial Tumors |
| title_full | Study of Surrogate Immunohistochemical Markers IDH1, ATRX, BRAF V600E, and p53 Mutation in Astrocytic and Oligodendroglial Tumors |
| title_fullStr | Study of Surrogate Immunohistochemical Markers IDH1, ATRX, BRAF V600E, and p53 Mutation in Astrocytic and Oligodendroglial Tumors |
| title_full_unstemmed | Study of Surrogate Immunohistochemical Markers IDH1, ATRX, BRAF V600E, and p53 Mutation in Astrocytic and Oligodendroglial Tumors |
| title_short | Study of Surrogate Immunohistochemical Markers IDH1, ATRX, BRAF V600E, and p53 Mutation in Astrocytic and Oligodendroglial Tumors |
| title_sort | study of surrogate immunohistochemical markers idh1 atrx braf v600e and p53 mutation in astrocytic and oligodendroglial tumors |
| topic | astrocytoma oligodendroglioma glioblastoma isocitrate dehydrogenase |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1743265 |
| work_keys_str_mv | AT santoshsharma studyofsurrogateimmunohistochemicalmarkersidh1atrxbrafv600eandp53mutationinastrocyticandoligodendroglialtumors AT kusummathur studyofsurrogateimmunohistochemicalmarkersidh1atrxbrafv600eandp53mutationinastrocyticandoligodendroglialtumors AT alkamittal studyofsurrogateimmunohistochemicalmarkersidh1atrxbrafv600eandp53mutationinastrocyticandoligodendroglialtumors AT meelmukta studyofsurrogateimmunohistochemicalmarkersidh1atrxbrafv600eandp53mutationinastrocyticandoligodendroglialtumors AT arpitajindal studyofsurrogateimmunohistochemicalmarkersidh1atrxbrafv600eandp53mutationinastrocyticandoligodendroglialtumors AT mukeshkumar studyofsurrogateimmunohistochemicalmarkersidh1atrxbrafv600eandp53mutationinastrocyticandoligodendroglialtumors |