Relationship between Salivary Levels of Protein Carbonyl and Total Antioxidant Capacity and Prevalence of Dental Caries among Type 1 Diabetic Children: An Analytical Cross-Sectional Study
Introduction: We aimed to assess the possible relationship between dental caries prevalence and oxidative stress markers such as protein carbonyl (PC) and total antioxidant capacity (TAOC) of saliva among type 1 diabetic children. Methods: An analytical cross-sectional study was performed among 45 t...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Dental Hypotheses |
| Subjects: | |
| Online Access: | http://www.dentalhypotheses.com/article.asp?issn=2155-8213;year=2023;volume=14;issue=2;spage=59;epage=61;aulast=Obaid |
| _version_ | 1797649414690439168 |
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| author | Shahad Fahim Obaid Shahbaa Munther Marwa Hasan Abbas |
| author_facet | Shahad Fahim Obaid Shahbaa Munther Marwa Hasan Abbas |
| author_sort | Shahad Fahim Obaid |
| collection | DOAJ |
| description | Introduction: We aimed to assess the possible relationship between dental caries prevalence and oxidative stress markers such as protein carbonyl (PC) and total antioxidant capacity (TAOC) of saliva among type 1 diabetic children. Methods: An analytical cross-sectional study was performed among 45 type 1 diabetic children and compared with 45 healthy control children aged 10 to 12 years old. Dental caries was diagnosed and recorded using the decayed, missing, and filling index (DMFS/dmfs). Unstimulated salivary specimens were collected for evaluation of TAOC and PC using an enzyme-linked immune-sorbent assay (ELISA). A linear regression model and one-way ANOVA test were employed for data analysis using the R 4.3.0. Results: Salivary levels of TAOC and PC, having diabetes, and diabetes status (controlled or uncontrolled) were not statistically significant (P > 0.05) predicators regarding the prevalence of dental caries among type 1diabetic children. Conclusion: The diabetic status had a significant effect on salivary levels of TAOC and PC, but no significant effect on the prevalence of dental caries. |
| first_indexed | 2024-03-11T15:45:48Z |
| format | Article |
| id | doaj.art-223b45cdf06e4a27b512f7f67f7d0b4c |
| institution | Directory Open Access Journal |
| issn | 2155-8213 |
| language | English |
| last_indexed | 2024-03-11T15:45:48Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Dental Hypotheses |
| spelling | doaj.art-223b45cdf06e4a27b512f7f67f7d0b4c2023-10-26T06:27:40ZengWolters Kluwer Medknow PublicationsDental Hypotheses2155-82132023-01-01142596110.4103/denthyp.denthyp_44_23Relationship between Salivary Levels of Protein Carbonyl and Total Antioxidant Capacity and Prevalence of Dental Caries among Type 1 Diabetic Children: An Analytical Cross-Sectional StudyShahad Fahim ObaidShahbaa MuntherMarwa Hasan AbbasIntroduction: We aimed to assess the possible relationship between dental caries prevalence and oxidative stress markers such as protein carbonyl (PC) and total antioxidant capacity (TAOC) of saliva among type 1 diabetic children. Methods: An analytical cross-sectional study was performed among 45 type 1 diabetic children and compared with 45 healthy control children aged 10 to 12 years old. Dental caries was diagnosed and recorded using the decayed, missing, and filling index (DMFS/dmfs). Unstimulated salivary specimens were collected for evaluation of TAOC and PC using an enzyme-linked immune-sorbent assay (ELISA). A linear regression model and one-way ANOVA test were employed for data analysis using the R 4.3.0. Results: Salivary levels of TAOC and PC, having diabetes, and diabetes status (controlled or uncontrolled) were not statistically significant (P > 0.05) predicators regarding the prevalence of dental caries among type 1diabetic children. Conclusion: The diabetic status had a significant effect on salivary levels of TAOC and PC, but no significant effect on the prevalence of dental caries.http://www.dentalhypotheses.com/article.asp?issn=2155-8213;year=2023;volume=14;issue=2;spage=59;epage=61;aulast=Obaidchildrendental carieselisa assayoxidative stressprotein carbonylsalivary biomarkerstotal antioxidant capacitytype 1 diabetes mellitus |
| spellingShingle | Shahad Fahim Obaid Shahbaa Munther Marwa Hasan Abbas Relationship between Salivary Levels of Protein Carbonyl and Total Antioxidant Capacity and Prevalence of Dental Caries among Type 1 Diabetic Children: An Analytical Cross-Sectional Study Dental Hypotheses children dental caries elisa assay oxidative stress protein carbonyl salivary biomarkers total antioxidant capacity type 1 diabetes mellitus |
| title | Relationship between Salivary Levels of Protein Carbonyl and Total Antioxidant Capacity and Prevalence of Dental Caries among Type 1 Diabetic Children: An Analytical Cross-Sectional Study |
| title_full | Relationship between Salivary Levels of Protein Carbonyl and Total Antioxidant Capacity and Prevalence of Dental Caries among Type 1 Diabetic Children: An Analytical Cross-Sectional Study |
| title_fullStr | Relationship between Salivary Levels of Protein Carbonyl and Total Antioxidant Capacity and Prevalence of Dental Caries among Type 1 Diabetic Children: An Analytical Cross-Sectional Study |
| title_full_unstemmed | Relationship between Salivary Levels of Protein Carbonyl and Total Antioxidant Capacity and Prevalence of Dental Caries among Type 1 Diabetic Children: An Analytical Cross-Sectional Study |
| title_short | Relationship between Salivary Levels of Protein Carbonyl and Total Antioxidant Capacity and Prevalence of Dental Caries among Type 1 Diabetic Children: An Analytical Cross-Sectional Study |
| title_sort | relationship between salivary levels of protein carbonyl and total antioxidant capacity and prevalence of dental caries among type 1 diabetic children an analytical cross sectional study |
| topic | children dental caries elisa assay oxidative stress protein carbonyl salivary biomarkers total antioxidant capacity type 1 diabetes mellitus |
| url | http://www.dentalhypotheses.com/article.asp?issn=2155-8213;year=2023;volume=14;issue=2;spage=59;epage=61;aulast=Obaid |
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