pPe Op inhibits HGC-27 cell proliferation, migration and invasion by upregulating miR-30b-5p and down-regulating the Rac1/Cdc42 pathway

pPe Op inhibits HGC-27 cell proliferation, migration and invasion by upregulating miR-30b-5p and down-regulating the Rac1/Cdc42 pathway

Gastric cancer is the fifth most frequently occurring and the fourth most lethal malignant cancer worldwide. A bioactive protein (pPe Op) from Omphalia lapidescens exhibits significant inhibitory effects on gastric cancer cells. miRNA deep sequencing analysis...

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Bibliographic Details
Main Authors: Xu Wenjun, Fu Zhenjie, Xu Yuqin, Cheung Man Hei, Chen Yan, Lin Meiai, Wen Hang, Lv Hang, Liang Chun, Lou Jianshu, Chen Yitao
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-12-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
gastric cancer
miR-30b-5p
<italic>Omphalia lapidescens</italic> Schroet.
Rac1/Cdc42
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022193

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https://www.sciengine.com/doi/10.3724/abbs.2022193

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