HBV-Induced Immune Imbalance in the Development of HCC

HBV-Induced Immune Imbalance in the Development of HCC

Chronic hepatitis B virus (HBV) infection is one of the high-risk factors for human HCC. Despite the integration of virus DNA and the oncoprotein HBx, chronic necroinflammation and hepatocellular regeneration account for hepatocarcinogenesis. As a non-cytopathic virus, HBV is extensively recognized...

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Bibliographic Details
Main Authors: Yongyan Chen, Zhigang Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
HBV
immune dysfunction
HCC
adaptive immunity
innate immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02048/full

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