Superspreading of SARS-CoV-2 in the USA.
A number of epidemics, including the SARS-CoV-1 epidemic of 2002-2004, have been known to exhibit superspreading, in which a small fraction of infected individuals is responsible for the majority of new infections. The existence of superspreading implies a fat-tailed distribution of infectiousness (...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0248808 |
| _version_ | 1819012989682974720 |
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| author | Calvin Pozderac Brian Skinner |
| author_facet | Calvin Pozderac Brian Skinner |
| author_sort | Calvin Pozderac |
| collection | DOAJ |
| description | A number of epidemics, including the SARS-CoV-1 epidemic of 2002-2004, have been known to exhibit superspreading, in which a small fraction of infected individuals is responsible for the majority of new infections. The existence of superspreading implies a fat-tailed distribution of infectiousness (new secondary infections caused per day) among different individuals. Here, we present a simple method to estimate the variation in infectiousness by examining the variation in early-time growth rates of new cases among different subpopulations. We use this method to estimate the mean and variance in the infectiousness, β, for SARS-CoV-2 transmission during the early stages of the pandemic within the United States. We find that σβ/μβ ≳ 3.2, where μβ is the mean infectiousness and σβ its standard deviation, which implies pervasive superspreading. This result allows us to estimate that in the early stages of the pandemic in the USA, over 81% of new cases were a result of the top 10% of most infectious individuals. |
| first_indexed | 2024-12-21T01:52:49Z |
| format | Article |
| id | doaj.art-224039a926514f8ca5ee4f625fe05204 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-21T01:52:49Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-224039a926514f8ca5ee4f625fe052042022-12-21T19:19:51ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01163e024880810.1371/journal.pone.0248808Superspreading of SARS-CoV-2 in the USA.Calvin PozderacBrian SkinnerA number of epidemics, including the SARS-CoV-1 epidemic of 2002-2004, have been known to exhibit superspreading, in which a small fraction of infected individuals is responsible for the majority of new infections. The existence of superspreading implies a fat-tailed distribution of infectiousness (new secondary infections caused per day) among different individuals. Here, we present a simple method to estimate the variation in infectiousness by examining the variation in early-time growth rates of new cases among different subpopulations. We use this method to estimate the mean and variance in the infectiousness, β, for SARS-CoV-2 transmission during the early stages of the pandemic within the United States. We find that σβ/μβ ≳ 3.2, where μβ is the mean infectiousness and σβ its standard deviation, which implies pervasive superspreading. This result allows us to estimate that in the early stages of the pandemic in the USA, over 81% of new cases were a result of the top 10% of most infectious individuals.https://doi.org/10.1371/journal.pone.0248808 |
| spellingShingle | Calvin Pozderac Brian Skinner Superspreading of SARS-CoV-2 in the USA. PLoS ONE |
| title | Superspreading of SARS-CoV-2 in the USA. |
| title_full | Superspreading of SARS-CoV-2 in the USA. |
| title_fullStr | Superspreading of SARS-CoV-2 in the USA. |
| title_full_unstemmed | Superspreading of SARS-CoV-2 in the USA. |
| title_short | Superspreading of SARS-CoV-2 in the USA. |
| title_sort | superspreading of sars cov 2 in the usa |
| url | https://doi.org/10.1371/journal.pone.0248808 |
| work_keys_str_mv | AT calvinpozderac superspreadingofsarscov2intheusa AT brianskinner superspreadingofsarscov2intheusa |