Clinical experience with a shape memory polymer peripheral vascular embolisation plug: a case series
Abstract Background Shape memory polymers are materials that are manufactured in a certain shape, can be stored in a temporary deformed shape, and then return to – or remember – their original shape upon exposure to external stimuli such as temperature and moisture. This property lends itself to app...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2021-03-01
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| Series: | CVIR Endovascular |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s42155-021-00214-w |
| _version_ | 1818649130784784384 |
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| author | Robert A. Morgan Ian Loftus Lakshmi Ratnam Raj Das Leto Mailli Mohamad S. Hamady Kyriakos Lobotesis |
| author_facet | Robert A. Morgan Ian Loftus Lakshmi Ratnam Raj Das Leto Mailli Mohamad S. Hamady Kyriakos Lobotesis |
| author_sort | Robert A. Morgan |
| collection | DOAJ |
| description | Abstract Background Shape memory polymers are materials that are manufactured in a certain shape, can be stored in a temporary deformed shape, and then return to – or remember – their original shape upon exposure to external stimuli such as temperature and moisture. This property lends itself to application in endovascular medical devices. Peripheral vasculature embolisation devices incorporating this novel technology have become commercially available and this case series, where the data were collected as part of a post market registry, outlines initial clinical experience with these novel devices. Results Eight cases are described in this series. The disease state/conditions for which embolisation was indicated were right common iliac artery aneurysms (n = 3), a type II endoleak into the thoracic aorta following thoracic endovascular aneurysm repair (n = 1), a left inferior gluteal artery aneurysm (n = 1), left internal iliac artery aneurysms (n = 2), and a case of splenomegaly, where splenectomy was planned after the embolisation procedure (n = 1). Target arteries were 5–10 mm in diameter. In each case, at least one IMPEDE Embolization Plug (IMP-Device) of an appropriate diameter was used. All procedures were technically successful and target vessel thrombosis was achieved in all cases. Follow-up imaging available during the 45–90-day data collection timeframe showed sustained vessel occlusion. This case series includes examples of situations commonly encountered when embolising the peripheral vasculature, namely, the use of one or multiple devices in a single vessel and in combination with the use of other embolic devices (e.g., microcoils, gelatin sponge, and PVA particles) in the same case. There were no adverse events related to the specific use of the device. Conclusions This small series illustrates the safety and efficacy of this novel sponge-based embolic device for the embolisation of small and medium sized arteries and further experience will demonstrate the utility of the shape memory polymer devices. |
| first_indexed | 2024-12-17T01:29:26Z |
| format | Article |
| id | doaj.art-224262565320422a8c51a56d34856cc9 |
| institution | Directory Open Access Journal |
| issn | 2520-8934 |
| language | English |
| last_indexed | 2024-12-17T01:29:26Z |
| publishDate | 2021-03-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | CVIR Endovascular |
| spelling | doaj.art-224262565320422a8c51a56d34856cc92022-12-21T22:08:36ZengSpringerOpenCVIR Endovascular2520-89342021-03-01411910.1186/s42155-021-00214-wClinical experience with a shape memory polymer peripheral vascular embolisation plug: a case seriesRobert A. Morgan0Ian Loftus1Lakshmi Ratnam2Raj Das3Leto Mailli4Mohamad S. Hamady5Kyriakos Lobotesis6Department of Radiology, St. George’s University Hospitals NHS Foundation TrustVascular Institute, St. George’s Healthcare NHS TrustDepartment of Radiology, St. George’s University Hospitals NHS Foundation TrustDepartment of Radiology, St. George’s University Hospitals NHS Foundation TrustInterventional Radiology, Guy’s and St Thomas’ NHS Foundation TrustInterventional Radiology, Imperial College-London-St. Mary’s CampusNeuroradiology, Charing Cross HospitalAbstract Background Shape memory polymers are materials that are manufactured in a certain shape, can be stored in a temporary deformed shape, and then return to – or remember – their original shape upon exposure to external stimuli such as temperature and moisture. This property lends itself to application in endovascular medical devices. Peripheral vasculature embolisation devices incorporating this novel technology have become commercially available and this case series, where the data were collected as part of a post market registry, outlines initial clinical experience with these novel devices. Results Eight cases are described in this series. The disease state/conditions for which embolisation was indicated were right common iliac artery aneurysms (n = 3), a type II endoleak into the thoracic aorta following thoracic endovascular aneurysm repair (n = 1), a left inferior gluteal artery aneurysm (n = 1), left internal iliac artery aneurysms (n = 2), and a case of splenomegaly, where splenectomy was planned after the embolisation procedure (n = 1). Target arteries were 5–10 mm in diameter. In each case, at least one IMPEDE Embolization Plug (IMP-Device) of an appropriate diameter was used. All procedures were technically successful and target vessel thrombosis was achieved in all cases. Follow-up imaging available during the 45–90-day data collection timeframe showed sustained vessel occlusion. This case series includes examples of situations commonly encountered when embolising the peripheral vasculature, namely, the use of one or multiple devices in a single vessel and in combination with the use of other embolic devices (e.g., microcoils, gelatin sponge, and PVA particles) in the same case. There were no adverse events related to the specific use of the device. Conclusions This small series illustrates the safety and efficacy of this novel sponge-based embolic device for the embolisation of small and medium sized arteries and further experience will demonstrate the utility of the shape memory polymer devices.https://doi.org/10.1186/s42155-021-00214-wShape memory polymerPeripheral embolisationVascular plug |
| spellingShingle | Robert A. Morgan Ian Loftus Lakshmi Ratnam Raj Das Leto Mailli Mohamad S. Hamady Kyriakos Lobotesis Clinical experience with a shape memory polymer peripheral vascular embolisation plug: a case series CVIR Endovascular Shape memory polymer Peripheral embolisation Vascular plug |
| title | Clinical experience with a shape memory polymer peripheral vascular embolisation plug: a case series |
| title_full | Clinical experience with a shape memory polymer peripheral vascular embolisation plug: a case series |
| title_fullStr | Clinical experience with a shape memory polymer peripheral vascular embolisation plug: a case series |
| title_full_unstemmed | Clinical experience with a shape memory polymer peripheral vascular embolisation plug: a case series |
| title_short | Clinical experience with a shape memory polymer peripheral vascular embolisation plug: a case series |
| title_sort | clinical experience with a shape memory polymer peripheral vascular embolisation plug a case series |
| topic | Shape memory polymer Peripheral embolisation Vascular plug |
| url | https://doi.org/10.1186/s42155-021-00214-w |
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