Primary extranodal lymphomas - spectrum of distribution and morphology with immunophenotyping: A 3-year institutional study
Background: Malignant lymphomas arising in extranodal sites are intriguing. The histological types of lymphomas vary from one site to another. This study is undertaken to diagnose and categorize extranodal lymphomas using histochemistry and immunohistochemistry (IHC). Materials and Methods: Formalin...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Medical Journal of Dr. D.Y. Patil University |
| Subjects: | |
| Online Access: | http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2015;volume=8;issue=2;spage=138;epage=143;aulast=Aparna |
| _version_ | 1798045294385954816 |
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| author | Chinnam Aparna Inuganti Venkata Renuka Muthyala Rajani Garikapati Sailabala Parvatala Annapurna |
| author_facet | Chinnam Aparna Inuganti Venkata Renuka Muthyala Rajani Garikapati Sailabala Parvatala Annapurna |
| author_sort | Chinnam Aparna |
| collection | DOAJ |
| description | Background: Malignant lymphomas arising in extranodal sites are intriguing. The histological types of lymphomas vary from one site to another. This study is undertaken to diagnose and categorize extranodal lymphomas using histochemistry and immunohistochemistry (IHC). Materials and Methods: Formalin processed paraffin blocks and hematoxylin and eosin stained sections were used for routine histology. IHC was done in all cases. Results: We have encountered 31 cases of extra nodal lymphomas over a period of 3 years. The tumors occurred at different sites, including brain, nasopharynx, nose, gastrointestinal tract, thyroid, bone, testis, breast, lung, vagina, and skin. Majority of the cases were B-cell lymphomas, while four cases were T-cell lymphomas. Among the B-cell lymphomas diffuse large B-cell lymphoma was the most common variant. Conclusion: This study reiterates the key role of IHC particularly when the differential diagnosis includes an undifferentiated epithelial malignancy and a high-grade lymphoma in the extranodal sites as the treatment modalities and prognosis are different. |
| first_indexed | 2024-04-11T23:18:28Z |
| format | Article |
| id | doaj.art-22459c5343354eaab5f2405cc968be63 |
| institution | Directory Open Access Journal |
| issn | 0975-2870 |
| language | English |
| last_indexed | 2024-04-11T23:18:28Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Medical Journal of Dr. D.Y. Patil University |
| spelling | doaj.art-22459c5343354eaab5f2405cc968be632022-12-22T03:57:32ZengWolters Kluwer Medknow PublicationsMedical Journal of Dr. D.Y. Patil University0975-28702015-01-018213814310.4103/0975-2870.153137Primary extranodal lymphomas - spectrum of distribution and morphology with immunophenotyping: A 3-year institutional studyChinnam AparnaInuganti Venkata RenukaMuthyala RajaniGarikapati SailabalaParvatala AnnapurnaBackground: Malignant lymphomas arising in extranodal sites are intriguing. The histological types of lymphomas vary from one site to another. This study is undertaken to diagnose and categorize extranodal lymphomas using histochemistry and immunohistochemistry (IHC). Materials and Methods: Formalin processed paraffin blocks and hematoxylin and eosin stained sections were used for routine histology. IHC was done in all cases. Results: We have encountered 31 cases of extra nodal lymphomas over a period of 3 years. The tumors occurred at different sites, including brain, nasopharynx, nose, gastrointestinal tract, thyroid, bone, testis, breast, lung, vagina, and skin. Majority of the cases were B-cell lymphomas, while four cases were T-cell lymphomas. Among the B-cell lymphomas diffuse large B-cell lymphoma was the most common variant. Conclusion: This study reiterates the key role of IHC particularly when the differential diagnosis includes an undifferentiated epithelial malignancy and a high-grade lymphoma in the extranodal sites as the treatment modalities and prognosis are different.http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2015;volume=8;issue=2;spage=138;epage=143;aulast=AparnaB-cell lymphomadiffuse large B-cell lymphomaextranodallymphomaT-cell lymphoma |
| spellingShingle | Chinnam Aparna Inuganti Venkata Renuka Muthyala Rajani Garikapati Sailabala Parvatala Annapurna Primary extranodal lymphomas - spectrum of distribution and morphology with immunophenotyping: A 3-year institutional study Medical Journal of Dr. D.Y. Patil University B-cell lymphoma diffuse large B-cell lymphoma extranodal lymphoma T-cell lymphoma |
| title | Primary extranodal lymphomas - spectrum of distribution and morphology with immunophenotyping: A 3-year institutional study |
| title_full | Primary extranodal lymphomas - spectrum of distribution and morphology with immunophenotyping: A 3-year institutional study |
| title_fullStr | Primary extranodal lymphomas - spectrum of distribution and morphology with immunophenotyping: A 3-year institutional study |
| title_full_unstemmed | Primary extranodal lymphomas - spectrum of distribution and morphology with immunophenotyping: A 3-year institutional study |
| title_short | Primary extranodal lymphomas - spectrum of distribution and morphology with immunophenotyping: A 3-year institutional study |
| title_sort | primary extranodal lymphomas spectrum of distribution and morphology with immunophenotyping a 3 year institutional study |
| topic | B-cell lymphoma diffuse large B-cell lymphoma extranodal lymphoma T-cell lymphoma |
| url | http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2015;volume=8;issue=2;spage=138;epage=143;aulast=Aparna |
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