A post-transcriptional regulatory landscape of aging in the female mouse hippocampus

A post-transcriptional regulatory landscape of aging in the female mouse hippocampus

Aging is associated with substantial physiological changes and constitutes a major risk factor for neurological disorders including dementia. Alterations in gene expression upon aging have been extensively studied; however, an in-depth characterization of post-transcriptional regulatory events remai...

Full description

Bibliographic Details
Main Authors:	Raphaelle Winsky-Sommerer, Helen A. King, Valentina Iadevaia, Carla Möller-Levet, André P. Gerber
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Series:	Frontiers in Aging Neuroscience
Subjects:	brain translatome transcriptome alternative splicing RNA-binding protein Polysome analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2023.1119873/full

Similar Items

Widespread uncoupling between transcriptome and translatome variations after a stimulus in mammalian cells
by: Tebaldi Toma, et al.
Published: (2012-06-01)

Selective translational usage of TSS and core promoters revealed by translatome sequencing
by: Hua Li, et al.
Published: (2019-04-01)

Bridging the gap: parallel profiling of ribosome associated and total RNA species can identify transcriptional regulatory mechanisms of plants in spaceflight
by: Eric S. Land, et al.
Published: (2023-12-01)

Different Regulatory Modes of Synechocystis sp. PCC 6803 in Response to Photosynthesis Inhibitory Conditions
by: Sang-Hyeok Cho, et al.
Published: (2021-12-01)

Translation control can shape TP53-dependent cell fate
by: Dario Rizzotto, et al.
Published: (2020-09-01)

Transcriptional and translational landscape fine-tune genome annotation and explores translation control in cotton
by: Ghulam Qanmber, et al.
Published: (2024-04-01)

Translatome analysis of tuberous sclerosis complex 1 patient-derived neural progenitor cells reveals rapamycin-dependent and independent alterations
by: Inci S. Aksoylu, et al.
Published: (2023-10-01)

Efficient Detection of the Alternative Spliced Human Proteome Using Translatome Sequencing
by: Chun Wu, et al.
Published: (2022-06-01)

Data on translatome analysis of Mycoplasma gallisepticum
by: G.Y. Fisunov, et al.
Published: (2016-12-01)

Ribosome profiling reveals differences in global translational vs transcriptional gene expression changes during early Candida albicans biofilm formation
by: Vasanthakrishna Mundodi, et al.
Published: (2025-03-01)

Alternative splicing events driven by altered levels of GEMIN5 undergo translation
by: Rosario Francisco-Velilla, et al.
Published: (2024-12-01)

Multi-omic profiling of MYCN-amplified neuroblastoma cell-lines
by: Erik Dassi, et al.
Published: (2015-12-01)

Functional Genomics of Axons and Synapses to Understand Neurodegenerative Diseases
by: Andres Di Paolo, et al.
Published: (2021-06-01)

The regulatory role of alternative splicing in inflammatory bowel disease
by: Jianli Zhou, et al.
Published: (2023-04-01)

The Enrichment of miRNA-Targeted mRNAs in Translationally Less Active over More Active Polysomes
by: Tingzeng Wang, et al.
Published: (2023-12-01)

Splicing of Friend murine leukemia virus env-mRNA enhances its ability to form polysomes
by: Akihito eMachinaga, et al.
Published: (2016-02-01)

Analysis of Thioredoxins and Glutaredoxins in Soybean: Evidence of Translational Regulation under Water Restriction
by: María Martha Sainz, et al.
Published: (2022-08-01)

When pitch adds to volume: coregulation of transcript diversity predicts gene function
by: Alejandro Cáceres, et al.
Published: (2018-12-01)

Water deficit response in nodulated soybean roots: a comprehensive transcriptome and translatome network analysis
by: María Martha Sainz, et al.
Published: (2024-06-01)

A translatome-transcriptome multi-omics gene regulatory network reveals the complicated functional landscape of maize
by: Wanchao Zhu, et al.
Published: (2023-03-01)

Widespread translational control contributes to the regulation of Arabidopsis photomorphogenesis
by: Ming‐Jung Liu, et al.
Published: (2012-01-01)

Comparison of Alternative Splicing Landscapes Revealed by Long-Read Sequencing in Hepatocyte-Derived HepG2 and Huh7 Cultured Cells and Human Liver Tissue
by: Anna Kozlova, et al.
Published: (2023-12-01)

Combined transcriptomics and proteomics unveil the impact of vitamin C in modulating specific protein abundance in the mouse liver
by: Lucie Aumailley, et al.
Published: (2024-05-01)

Comprehensive and scalable quantification of splicing differences with MntJULiP
by: Guangyu Yang, et al.
Published: (2022-09-01)

Translatome and transcriptome profiling of neonatal mice hippocampus exposed to sevoflurane anesthesia
by: Menghan Wang, et al.
Published: (2024-05-01)

Analysis of post-transcriptional regulatory signatures and immune cell subsets in premature ovarian insufficiency based on full-length transcriptome
by: Zhaoyang Yu, et al.
Published: (2025-02-01)

RNA-Binding Protein Rbm24 as a Multifaceted Post-Transcriptional Regulator of Embryonic Lineage Differentiation and Cellular Homeostasis
by: Raphaëlle Grifone, et al.
Published: (2020-08-01)

Multi-omics analysis of functional substances and expression verification in cashmere fineness
by: Yanan Xu, et al.
Published: (2023-11-01)

Spatiotemporal Regulation of Transcript Isoform Expression in the Hippocampus
by: Joun Park, et al.
Published: (2021-07-01)

FUCHS—towards full circular RNA characterization using RNAseq
by: Franziska Metge, et al.
Published: (2017-02-01)

Psoriasis-Specific RNA Isoforms Identified by RNA-seq Analysis of 173,446 Transcripts
by: Sulev Kõks, et al.
Published: (2016-10-01)

The Genetic Regulation of Alternative Splicing in Populus deltoides
by: Jerald D. Noble, et al.
Published: (2020-06-01)

A lipid-soluble antioxidant from polyallomer centrifuge tubes
by: Clyde E. Opliger, et al.
Published: (1974-05-01)

Alternative splicing in shaping the molecular landscape of the cochlea
by: Kwan Soo Kim, et al.
Published: (2023-03-01)

Ribosome and transcript copy numbers, polysome occupancy and enzyme dynamics in Arabidopsis
by: Maria Piques, et al.
Published: (2009-10-01)

A SLM2 Feedback Pathway Controls Cortical Network Activity and Mouse Behavior
by: Ingrid Ehrmann, et al.
Published: (2016-12-01)

The cap-binding complex modulates ABA-responsive transcript splicing during germination in barley (Hordeum vulgare)
by: Ewa Sybilska, et al.
Published: (2024-08-01)

Astonishing advances in mouse genetic tools for biomedical research
by: Walker Scot Jackson, et al.
Published: (2015-10-01)

Stable maternal proteins underlie distinct transcriptome, translatome, and proteome reprogramming during mouse oocyte-to-embryo transition
by: Hongmei Zhang, et al.
Published: (2023-07-01)

The landscape of human mutually exclusive splicing
by: Klas Hatje, et al.
Published: (2017-12-01)