mTOR modulates CD8+ T cell differentiation in mice with invasive pulmonary aspergillosis

CD8+ T cells are a vital component of the adaptive immune system and important for eliminating intracellular pathogens. Notably, mTOR activity is associated with CD8+ T effector memory (Tem) cell differentiation in fungal infections. This study investigates the molecular mechanisms of CD8+ Tem cell...

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Bibliographic Details
Main Authors: Wang Hao, Xiao Yu, Su Longxiang, Cui Na, Liu Dawei
Format: Article
Language:English
Published: De Gruyter 2018-05-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2018-0018