The Suitability of Latex Particles to Evaluate Critical Process Parameters in Steric Exclusion Chromatography

The Suitability of Latex Particles to Evaluate Critical Process Parameters in Steric Exclusion Chromatography

The steric exclusion chromatography (SXC) is a rather new method for the purification of large biomolecules and biological nanoparticles based on the principles of precipitation. The mutual steric exclusion of a nonionic organic polymer, i.e., polyethylene glycol (PEG), induces target precipitation...

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Bibliographic Details
Main Authors: Friederike Eilts, Marleen Steger, Keven Lothert, Michael W. Wolff
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Membranes
Subjects:
aggregation
crowding out
downstream processing
pH
polyethylene glycol
SXC
Online Access:https://www.mdpi.com/2077-0375/12/5/488

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