Genomic analysis of transcriptional networks directing progression of cell states during MGE development

Genomic analysis of transcriptional networks directing progression of cell states during MGE development

Abstract Background Homeodomain (HD) transcription factor (TF) NKX2–1 critical for the regional specification of the medial ganglionic eminence (MGE) as well as promoting the GABAergic and cholinergic neuron fates via the induction of TFs such as LHX6 and LHX8. NKX2–1 defines MGE regional identity i...

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Bibliographic Details
Main Authors: Magnus Sandberg, Leila Taher, Jianxin Hu, Brian L. Black, Alex S. Nord, John L. R. Rubenstein
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Neural Development
Subjects:
TCF12
SOX
OCT
LHX
MEIS
Medial ganglionic eminence
Online Access:http://link.springer.com/article/10.1186/s13064-018-0119-4

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http://link.springer.com/article/10.1186/s13064-018-0119-4

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