Young-Onset Dementia with Lewy Bodies
Young-onset (< 65 years) dementia is a challenging clinical problem. A 61-year-old man visited our clinic because of a 2-year history of mild cognitive impairment of the executive disorder type. He was initially suspected of having young-onset Alzheimer’s disease due to the lack of motor si...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2018-12-01
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| Series: | Case Reports in Neurology |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/495748 |
| _version_ | 1818187108103225344 |
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| author | Yosuke Aiba Ryuji Sakakibara Tsuyoshi Ogata Ayako Iimura Keiichiro Terayama Keiko Suzuki Shuichi Katsuragawa Yuuki Kato Fuyuki Tateno Hitoshi Terada Tsutomu Inaoka Tomoya Nakatsuka |
| author_facet | Yosuke Aiba Ryuji Sakakibara Tsuyoshi Ogata Ayako Iimura Keiichiro Terayama Keiko Suzuki Shuichi Katsuragawa Yuuki Kato Fuyuki Tateno Hitoshi Terada Tsutomu Inaoka Tomoya Nakatsuka |
| author_sort | Yosuke Aiba |
| collection | DOAJ |
| description | Young-onset (< 65 years) dementia is a challenging clinical problem. A 61-year-old man visited our clinic because of a 2-year history of mild cognitive impairment of the executive disorder type. He was initially suspected of having young-onset Alzheimer’s disease due to the lack of motor signs or hippocampal atrophy by conventional brain MRI. However, he proved to have anosmia, erectile dysfunction, hypersexuality, constipation, REM sleep behavior disorder, and emotional lability; imaging findings included positive brain perfusion SPECT, nigrosome MRI, DAT scan, and MIBG myocardial scintigraphy. All these clinical imaging features led to the correct diagnosis of young-onset dementia with Lewy bodies (YOD-DLB). It is hoped that this case report will help facilitate a future prospective study to diagnose and follow YOD-DLB patients with the aim of determining appropriate management and care. |
| first_indexed | 2024-12-11T23:05:47Z |
| format | Article |
| id | doaj.art-225bdef22ccb499e9737f5ce35c6bc58 |
| institution | Directory Open Access Journal |
| issn | 1662-680X |
| language | English |
| last_indexed | 2024-12-11T23:05:47Z |
| publishDate | 2018-12-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Neurology |
| spelling | doaj.art-225bdef22ccb499e9737f5ce35c6bc582022-12-22T00:46:55ZengKarger PublishersCase Reports in Neurology1662-680X2018-12-0110336336810.1159/000495748495748Young-Onset Dementia with Lewy BodiesYosuke AibaRyuji SakakibaraTsuyoshi OgataAyako IimuraKeiichiro TerayamaKeiko SuzukiShuichi KatsuragawaYuuki KatoFuyuki TatenoHitoshi TeradaTsutomu InaokaTomoya NakatsukaYoung-onset (< 65 years) dementia is a challenging clinical problem. A 61-year-old man visited our clinic because of a 2-year history of mild cognitive impairment of the executive disorder type. He was initially suspected of having young-onset Alzheimer’s disease due to the lack of motor signs or hippocampal atrophy by conventional brain MRI. However, he proved to have anosmia, erectile dysfunction, hypersexuality, constipation, REM sleep behavior disorder, and emotional lability; imaging findings included positive brain perfusion SPECT, nigrosome MRI, DAT scan, and MIBG myocardial scintigraphy. All these clinical imaging features led to the correct diagnosis of young-onset dementia with Lewy bodies (YOD-DLB). It is hoped that this case report will help facilitate a future prospective study to diagnose and follow YOD-DLB patients with the aim of determining appropriate management and care.https://www.karger.com/Article/FullText/495748Young onsetDementia with Lewy bodiesMild cognitive impairmentMIBG myocardial scintigraphyDopamine transporter scan |
| spellingShingle | Yosuke Aiba Ryuji Sakakibara Tsuyoshi Ogata Ayako Iimura Keiichiro Terayama Keiko Suzuki Shuichi Katsuragawa Yuuki Kato Fuyuki Tateno Hitoshi Terada Tsutomu Inaoka Tomoya Nakatsuka Young-Onset Dementia with Lewy Bodies Case Reports in Neurology Young onset Dementia with Lewy bodies Mild cognitive impairment MIBG myocardial scintigraphy Dopamine transporter scan |
| title | Young-Onset Dementia with Lewy Bodies |
| title_full | Young-Onset Dementia with Lewy Bodies |
| title_fullStr | Young-Onset Dementia with Lewy Bodies |
| title_full_unstemmed | Young-Onset Dementia with Lewy Bodies |
| title_short | Young-Onset Dementia with Lewy Bodies |
| title_sort | young onset dementia with lewy bodies |
| topic | Young onset Dementia with Lewy bodies Mild cognitive impairment MIBG myocardial scintigraphy Dopamine transporter scan |
| url | https://www.karger.com/Article/FullText/495748 |
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