When intra-operative exploration is the only option, severe medically refractory trigeminal neuralgia

Introduction: Patients with trigeminal neuralgia (TN) are usually treated on an outpatient basis, and symptoms can be controlled using various medical therapeutic options. We present a case of severe TN with an acute on chronic flare, which was now refractory to a wide variety of medical options, ha...

Full description

Bibliographic Details
Main Authors: Jaskeerat Singh, Vidhi Mehta
Format: Article
Language:English
Published: Greater Baltimore Medical Center 2021-09-01
Series:Journal of Community Hospital Internal Medicine Perspectives
Subjects:
Online Access:http://dx.doi.org/10.1080/20009666.2021.1944570
_version_ 1797972705404780544
author Jaskeerat Singh
Vidhi Mehta
author_facet Jaskeerat Singh
Vidhi Mehta
author_sort Jaskeerat Singh
collection DOAJ
description Introduction: Patients with trigeminal neuralgia (TN) are usually treated on an outpatient basis, and symptoms can be controlled using various medical therapeutic options. We present a case of severe TN with an acute on chronic flare, which was now refractory to a wide variety of medical options, had a prolonged inpatient hospitalization, and ultimately required surgery with excellent results.Case: A 54-year-old Hispanic male was admitted with severe left-sided TN. His symptoms gradually became more pronounced and frequent to a point where he was unable to have a meaningful quality of life. A trial of gabapentin, phenytoin, opioids, and NSAIDs had also been unsuccessful before this hospitalization. He had three ER visits before he was finally hospitalized with intractable pain and unfortunately had begun to have suicidal thoughts. Various therapeutic interventions were tried, including escalating doses of opioids and local nerve blocks, but all non-surgical options failed to provide relief. Neurosurgical route was eventually approached, and patient underwent left retro mastoid suboccipital craniectomy. Intraoperatively, the left superior cerebellar artery was found to adhere to the inferior ventral aspect of the left trigeminal nerve root entry zone. Upon decompression patient’s symptoms resolved dramatically. Interestingly this vascular compression was not seen on multiple prior brain imaging.Conclusion: TN can severely affect someone’s quality of life. It often leads to severe anxiety and depression. Our case represents the importance of proceeding towards surgical options sooner rather than later. An early multi-disciplinary approach is warranted.
first_indexed 2024-04-11T03:52:44Z
format Article
id doaj.art-225fa73885c74277acc18af6cf0d158d
institution Directory Open Access Journal
issn 2000-9666
language English
last_indexed 2024-04-11T03:52:44Z
publishDate 2021-09-01
publisher Greater Baltimore Medical Center
record_format Article
series Journal of Community Hospital Internal Medicine Perspectives
spelling doaj.art-225fa73885c74277acc18af6cf0d158d2023-01-02T01:24:49ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662021-09-0111568668810.1080/20009666.2021.19445701944570When intra-operative exploration is the only option, severe medically refractory trigeminal neuralgiaJaskeerat Singh0Vidhi Mehta1Mid-Columbia Medical CenterMid-Columbia Medical Center Celilo Cancer CenterIntroduction: Patients with trigeminal neuralgia (TN) are usually treated on an outpatient basis, and symptoms can be controlled using various medical therapeutic options. We present a case of severe TN with an acute on chronic flare, which was now refractory to a wide variety of medical options, had a prolonged inpatient hospitalization, and ultimately required surgery with excellent results.Case: A 54-year-old Hispanic male was admitted with severe left-sided TN. His symptoms gradually became more pronounced and frequent to a point where he was unable to have a meaningful quality of life. A trial of gabapentin, phenytoin, opioids, and NSAIDs had also been unsuccessful before this hospitalization. He had three ER visits before he was finally hospitalized with intractable pain and unfortunately had begun to have suicidal thoughts. Various therapeutic interventions were tried, including escalating doses of opioids and local nerve blocks, but all non-surgical options failed to provide relief. Neurosurgical route was eventually approached, and patient underwent left retro mastoid suboccipital craniectomy. Intraoperatively, the left superior cerebellar artery was found to adhere to the inferior ventral aspect of the left trigeminal nerve root entry zone. Upon decompression patient’s symptoms resolved dramatically. Interestingly this vascular compression was not seen on multiple prior brain imaging.Conclusion: TN can severely affect someone’s quality of life. It often leads to severe anxiety and depression. Our case represents the importance of proceeding towards surgical options sooner rather than later. An early multi-disciplinary approach is warranted.http://dx.doi.org/10.1080/20009666.2021.1944570trigeminal neuralgiasevere casesurgeryneurovascular decompression
spellingShingle Jaskeerat Singh
Vidhi Mehta
When intra-operative exploration is the only option, severe medically refractory trigeminal neuralgia
Journal of Community Hospital Internal Medicine Perspectives
trigeminal neuralgia
severe case
surgery
neurovascular decompression
title When intra-operative exploration is the only option, severe medically refractory trigeminal neuralgia
title_full When intra-operative exploration is the only option, severe medically refractory trigeminal neuralgia
title_fullStr When intra-operative exploration is the only option, severe medically refractory trigeminal neuralgia
title_full_unstemmed When intra-operative exploration is the only option, severe medically refractory trigeminal neuralgia
title_short When intra-operative exploration is the only option, severe medically refractory trigeminal neuralgia
title_sort when intra operative exploration is the only option severe medically refractory trigeminal neuralgia
topic trigeminal neuralgia
severe case
surgery
neurovascular decompression
url http://dx.doi.org/10.1080/20009666.2021.1944570
work_keys_str_mv AT jaskeeratsingh whenintraoperativeexplorationistheonlyoptionseveremedicallyrefractorytrigeminalneuralgia
AT vidhimehta whenintraoperativeexplorationistheonlyoptionseveremedicallyrefractorytrigeminalneuralgia