Guided by the principles of microbiome engineering: Accomplishments and perspectives for environmental use
Abstract Although the accomplishments of microbiome engineering highlight its significance for the targeted manipulation of microbial communities, knowledge and technical gaps still limit the applications of microbiome engineering in biotechnology, especially for environmental use. Addressing the en...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-12-01
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| Series: | mLife |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/mlf2.12043 |
| _version_ | 1811170858040819712 |
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| author | Haiyang Hu Miaoxiao Wang Yiqun Huang Zhaoyong Xu Ping Xu Yong Nie Hongzhi Tang |
| author_facet | Haiyang Hu Miaoxiao Wang Yiqun Huang Zhaoyong Xu Ping Xu Yong Nie Hongzhi Tang |
| author_sort | Haiyang Hu |
| collection | DOAJ |
| description | Abstract Although the accomplishments of microbiome engineering highlight its significance for the targeted manipulation of microbial communities, knowledge and technical gaps still limit the applications of microbiome engineering in biotechnology, especially for environmental use. Addressing the environmental challenges of refractory pollutants and fluctuating environmental conditions requires an adequate understanding of the theoretical achievements and practical applications of microbiome engineering. Here, we review recent cutting‐edge studies on microbiome engineering strategies and their classical applications in bioremediation. Moreover, a framework is summarized for combining both top‐down and bottom‐up approaches in microbiome engineering toward improved applications. A strategy to engineer microbiomes for environmental use, which avoids the build‐up of toxic intermediates that pose a risk to human health, is suggested. We anticipate that the highlighted framework and strategy will be beneficial for engineering microbiomes to address difficult environmental challenges such as degrading multiple refractory pollutants and sustain the performance of engineered microbiomes in situ with indigenous microorganisms under fluctuating conditions. |
| first_indexed | 2024-04-10T17:03:43Z |
| format | Article |
| id | doaj.art-225fc6b58150477e938a8adddc2cd0fc |
| institution | Directory Open Access Journal |
| issn | 2770-100X |
| language | English |
| last_indexed | 2024-04-10T17:03:43Z |
| publishDate | 2022-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | mLife |
| spelling | doaj.art-225fc6b58150477e938a8adddc2cd0fc2023-02-06T07:06:42ZengWileymLife2770-100X2022-12-011438239810.1002/mlf2.12043Guided by the principles of microbiome engineering: Accomplishments and perspectives for environmental useHaiyang Hu0Miaoxiao Wang1Yiqun Huang2Zhaoyong Xu3Ping Xu4Yong Nie5Hongzhi Tang6State Key Laboratory of Microbial Metabolism, and School of Life Sciences & Biotechnology Shanghai Jiao Tong University Shanghai ChinaDepartment of Environmental Systems Science ETH Zürich Zürich SwitzerlandState Key Laboratory of Microbial Metabolism, and School of Life Sciences & Biotechnology Shanghai Jiao Tong University Shanghai ChinaState Key Laboratory of Microbial Metabolism, and School of Life Sciences & Biotechnology Shanghai Jiao Tong University Shanghai ChinaState Key Laboratory of Microbial Metabolism, and School of Life Sciences & Biotechnology Shanghai Jiao Tong University Shanghai ChinaCollege of Engineering Peking University Beijing ChinaState Key Laboratory of Microbial Metabolism, and School of Life Sciences & Biotechnology Shanghai Jiao Tong University Shanghai ChinaAbstract Although the accomplishments of microbiome engineering highlight its significance for the targeted manipulation of microbial communities, knowledge and technical gaps still limit the applications of microbiome engineering in biotechnology, especially for environmental use. Addressing the environmental challenges of refractory pollutants and fluctuating environmental conditions requires an adequate understanding of the theoretical achievements and practical applications of microbiome engineering. Here, we review recent cutting‐edge studies on microbiome engineering strategies and their classical applications in bioremediation. Moreover, a framework is summarized for combining both top‐down and bottom‐up approaches in microbiome engineering toward improved applications. A strategy to engineer microbiomes for environmental use, which avoids the build‐up of toxic intermediates that pose a risk to human health, is suggested. We anticipate that the highlighted framework and strategy will be beneficial for engineering microbiomes to address difficult environmental challenges such as degrading multiple refractory pollutants and sustain the performance of engineered microbiomes in situ with indigenous microorganisms under fluctuating conditions.https://doi.org/10.1002/mlf2.12043bioremediationenergy productionenvironmental microbiologymicrobiome engineering |
| spellingShingle | Haiyang Hu Miaoxiao Wang Yiqun Huang Zhaoyong Xu Ping Xu Yong Nie Hongzhi Tang Guided by the principles of microbiome engineering: Accomplishments and perspectives for environmental use mLife bioremediation energy production environmental microbiology microbiome engineering |
| title | Guided by the principles of microbiome engineering: Accomplishments and perspectives for environmental use |
| title_full | Guided by the principles of microbiome engineering: Accomplishments and perspectives for environmental use |
| title_fullStr | Guided by the principles of microbiome engineering: Accomplishments and perspectives for environmental use |
| title_full_unstemmed | Guided by the principles of microbiome engineering: Accomplishments and perspectives for environmental use |
| title_short | Guided by the principles of microbiome engineering: Accomplishments and perspectives for environmental use |
| title_sort | guided by the principles of microbiome engineering accomplishments and perspectives for environmental use |
| topic | bioremediation energy production environmental microbiology microbiome engineering |
| url | https://doi.org/10.1002/mlf2.12043 |
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